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3-Hydroxypyrazine-2-carboxamide
(CAS RN:55321-99-8 Product Number:H1485)

Structure

3-Hydroxypyrazine-2-carboxamide
Synonym T-1105

General Information

Product Number H1485

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Stock in other WH:2-3 Business Days
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Purity/Analysis Method >98.0%(HPLC)(T)
Grade
Storage Temperature
M.F. / M.W. C5H5N3O2=139.11
CAS RN 55321-99-8
Related CAS RN
MDL Number MFCD00233977
Packaging and Container
  • Product Details
  • Safety & Regulations
  • Reference & Application

Specification

Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %

Data of Reference

λmax 348(lit.)

References

Reaxys-RN 908163
PubChem SID 253660706

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P280
  • :Wear protective gloves, eye protection.
  • P302+P352+P332+P313+P362+P364
  • :If on skin: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Application

Viral RNA Polymerase Inhibitor

H1485

3-Hydroxypyrazine-2-carboxamide (T-1105) is reported as an antiviral compound with broad activity against influenza virus and diverse RNA viruses. Its ribose-5’-triphosphate is the active metabolite, and it is recognized by virus RNA polymerase as a substrate competing with guanosine 5'-triphosphate (GTP), giving inhibition of viral RNA synthesis. For your reference, favipiravir (T-705) [CAS: 259793-96-9], an antiviral agent, is an analog adding the 6-fluoro atom. (The product is for research purpose only.)

References

PubMed Literature

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