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TMS-BA [=N,O-Bis(trimethylsilyl)acetamide] (25% in Acetonitrile) [for Gas Chromatography]
(CAS RN:10416-59-8 Product Number:A5602)


Synonym N,O-Bis(trimethylsilyl)acetamide (25% in Acetonitrile)
Synonym BSA (25% in Acetonitrile)

General Information

Product Number A5602

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Purity/Analysis Method
Storage Temperature 0-10°C
M.F. / M.W.
CAS RN 10416-59-8
Related CAS RN
MDL Number MFCD00008270
Packaging and Container 5mL-Vial (View image)
  • Product Details
  • Safety & Regulations


Appearance Colorless to Light yellow clear liquid
Effect test of TMS derivatization Effective as derivatization agent DL-Threonine
High boiling impurity of Silylation agent No impurity higher than Isopropyl myristate(50 ppm) after 5 min + hold up time


Reaxys-RN 1306669
PubChem SID 87563204
F&F 3,23
EC Number 233-892-7


Signal Word Danger
Hazard Statements
  • H225
  • :Highly flammable liquid and vapour.
  • H302
  • :Harmful if swallowed.
  • H311
  • :Toxic in contact with skin.
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
  • H341
  • :Suspected of causing genetic defects.
  • H370
  • :Causes damage to Respiratory System, Central Nervous System.
  • H373
  • :May cause damage to Liver, Blood (System), Respiratory System, Kidney, Central Nervous System through prolonged or repeated exposure.
Precautionary Statements
  • P210
  • :Keep away from heat/sparks/open flames/hot surfaces. – No smoking.
  • P260
  • :Do not breathe mist, vapours or spray.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P302+P352+P312+P361+P364
  • :IF ON SKIN: Wash with plenty of soap and water. Call a POISON CENTER or doctor if you feel unwell. Take off immediately all contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.
  • P308+P311
  • :If exposed or concerned: Call a POISON CENTER or doctor.

Transport Information

UN Number 1992
Class 3/6.1
Packing Group II
HS Number 3822000000


Trimethylsilylating Reagent for GC


Experimental procedure:
Approx. 1 mg of a sample and TMS-BA (1 mL) are placed in a dry vial, and the vial is tightly sealed and allowed to react by shaking or heating.

PubMed Literature

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