Home >   Products   >  Advanced Search

N,O-Bis(trimethylsilyl)acetamide Kit TMS-BA (25% in Acetonitrile) 1 mL × 8 / Reaction vial, capacity 2 mL × 8 [Trimethylsilylating Reagent, for NH2 compounds]
(CAS RN:10416-59-8 Product Number:T0691)


N,O-Bis(trimethylsilyl)acetamide Kit
Synonym BSA Kit
Synonym TMS-BA Kit

General Information

Product Number T0691

* Items available from stock in Japan will be delivered in 10 business days.
* Please contact us if you need further information.
(Sales Dept Tel: +32 (0)3 735 07 00 E-mail: Sales-EU@TCIchemicals.com)
* To send your quote request for bulk quantities, please click on the “Request Bulk Quotation” button. Please note that for some of our products we cannot offer bulk quantities.
* TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

Purity/Analysis Method
Storage Temperature 0-10°C
M.F. / M.W.
CAS RN 10416-59-8
Related CAS RN
MDL Number MFCD00008270
Packaging and Container 1kit-Vial (View image)
  • Product Details
  • Safety & Regulations


Appearance Colorless to Light yellow clear liquid
Effect test of TMS derivatization Effective as derivatization agent DL-Threonine


Reaxys-RN 2206090
PubChem SID 87576562
EC Number 233-892-7


Signal Word Danger
Hazard Statements
  • H225
  • :Highly flammable liquid and vapour.
  • H302
  • :Harmful if swallowed.
  • H311
  • :Toxic in contact with skin.
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
  • H341
  • :Suspected of causing genetic defects.
  • H370
  • :Causes damage to Respiratory System, Central Nervous System.
  • H373
  • :May cause damage to Liver, Blood (System), Respiratory System, Kidney, Central Nervous System through prolonged or repeated exposure.
Precautionary Statements
  • P210
  • :Keep away from heat/sparks/open flames/hot surfaces. – No smoking.
  • P260
  • :Do not breathe mist, vapours or spray.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P302+P352+P312+P361+P364
  • :IF ON SKIN: Wash with plenty of soap and water. Call a POISON CENTER or doctor if you feel unwell. Take off immediately all contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.
  • P308+P311
  • :If exposed or concerned: Call a POISON CENTER or doctor.

Transport Information

UN Number 1992
Class 3/6.1
Packing Group II
HS Number 2931399090


Trimethylsilylating Reagent for GC Derivatization


Experimental procedure: ca. 1 mg of sample and 1 mL of TMS-BA is placed into a dry vessel (about 2 mL of vial is preferable). After sealing the vessel, the reaction is proceeded by shaking or heating (e.g. for leucine, threonine, by heating for 15 min at 125 °C) to result a transparent solution. And then it is directly injected into GC.


Reactivity of Trimethylsilylating Reagents : Trimethylsilylation of Alcohols

B0511, B0510, B0911, T0691


  • Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols
    • P. G. M. Wuts, in Greene’s Protective Groups in Organic Synthesis, 5th ed., ed. by P. G. M. Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17.

PubMed Literature

Page Top