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Mycophenolate Mofetil
(CAS RN:128794-94-5 Product Number:M2387)

Structure

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Mycophenolate Mofetil
Synonym (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid 2-(4-Morpholinyl)ethyl Ester
Synonym 2-(4-Morpholinyl)ethyl (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoate

General Information

Product Number M2387

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C23H31NO7=433.50
CAS RN 128794-94-5
Related CAS RN
MDL Number MFCD00867568
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 94.0 to 98.0 deg-C

References

Reaxys-RN 14419508
PubChem SID 253661600
Merck Index(14) 6327
RTECS# MP7746700

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H351
  • :Suspected of causing cancer.
  • H360FD
  • :May damage fertility. May damage the unborn child.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.
  • P405
  • :Store locked up.

Transport Information

HS Number 2934999090

Application

Mycophenolate mofetil (MMF): An Inhibitor of Inosine Monophosphate Dehydrogenase (IMPDH), Needed for the Growth of T Cells and B Cells

Mycophenolate mofetil (abbrev: MMF) is an ester prodrug of the active immunosuppressant mycophenolic acid (MPA)[M2216] . MPA is a noncompetitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH), an important enzyme in the de novo synthesis of guanosine nucleotides in T and B lymphocytes. MMF is a widely used component of immunosuppressive regimens in organ transplantation. (The product is for research purpose only.)

References

PubMed Literature

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