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Tamoxifen Citrate
(CAS RN:54965-24-1 Product Number:T2510)

Structure

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Tamoxifen Citrate
Synonym (Z)-1-(4-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene Citrate

General Information

Product Number T2510

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature 0-10°C
M.F. / M.W. C26H29NO·C6H8O7=563.65
CAS RN 54965-24-1
Related CAS RN 10540-29-1
MDL Number MFCD00058321
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %

Data of Reference

mp 142°C(dec.)(lit.)

References

Reaxys-RN 8888650
PubChem SID 87560062
Merck Index(14) 9048
RTECS# KH2387000
EC Number 259-415-2

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H350
  • :May cause cancer.
  • H360FD
  • :May damage fertility. May damage the unborn child.
  • H362
  • :May cause harm to breast-fed children.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P260
  • :Do not breathe dusts or mists.
  • P263
  • :Avoid contact during pregnancy/while nursing.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.

Transport Information

HS Number 2921490090

Application

Tamoxifen Citrate: Selective Estrogen Receptor Modulator (SERM)

Tamoxifen citrate is a widely used nonsteroidal anti-estrogen agent for the treatment of hormone-dependent breast cancer. Tamoxifen is a prodrug and extensively metabolized by cytochrome P450 (CYP450) enzymes into active metabolites including 4-hydroxytamoxifen and endoxifen (4-hydroxy-N-desmethyltamoxifen). They act as an estrogen receptor antagonist in breast tissue. Tamoxifen is commonly referred to as a selective estrogen receptor modulator (SERM), since it behaves as an estrogen receptor agonist in other tissues. (The product is for research purpose only.)

References

PubMed Literature

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