Home >   Products   >  Advanced Search

Boron Trifluoride - Ethyl Ether Complex
(CAS RN:109-63-7 Product Number:B0527)

Structure

Boron Trifluoride - Ethyl Ether Complex

General Information

Product Number B0527

* Items available from stock in Japan will be delivered in 1-2 weeks.
* Please contact us if you need further information.
(Sales Dept Tel: 800-423-8616 / 503-283-1681 E-mail: Sales-US@TCIchemicals.com)
* To send your quote request for bulk quantities, please click on the “Request Bulk Quotation” button. Please note that we cannot offer bulk quantities for some products.
* TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

Purity/Analysis Method >98.0%(W)
Storage Temperature
M.F. / M.W. BF3·C4H10O=141.93
CAS RN 109-63-7
Related CAS RN
MDL Number MFCD00013194
  • Product Details
  • Safety & Regulations
  • Reference & Application

Specification

Purity(Gravimetric Method) 98.0 to 102.0 %
Specific gravity (20/20) 1.1250 to 1.1320
Refractive index n20/D 1.3430 to 1.3470

Data of Reference

mp -60°C(lit.)
bp 124°C

References

Reaxys-RN 3909607
PubChem SID 87563549
Merck Index(14) 1350
F&F 9,64

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H226
  • :Flammable liquid and vapor.
  • H302+H312
  • :Harmful in contact with skin and if swallowed.
  • H314
  • :Causes severe skin burns and eye damage.
Precautionary Statements
  • P210
  • :Keep away from heat, sparks, open flames and hot surfaces. – No smoking.
  • P233
  • :Keep container tightly closed.
  • P240
  • :Ground and bond container and receiving equipment.
  • P241+P242+P243
  • :Use explosion-proof electrical, ventilating and lighting equipment. Use only non-sparking tools. Take precautionary measures against static discharge.
  • P260
  • :Do not breathe dusts or mists.
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P301+P330+P331+P310
  • :If swallowed: Rinse mouth. Do NOT induce vomiting. Immediately call a poison center or doctor.
  • P303+P361+P353+P310+P363
  • :If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. Immediately call a poison center or doctor. Wash contaminated clothing before reuse.
  • P304+P340+P310
  • :If inhaled: Remove person to fresh air and keep comfortable for breathing. Immediately call a poison center or doctor.
  • P305+P351+P338+P310
  • :If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a poison center or doctor.
  • P370+P378
  • :In case of fire: Use dry chemical, dry sand or foam to extinguish.
  • P403+P235
  • :Store in a well-ventilated place. Keep cool.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents and container in accordance with local, regional, national regulations (e.g. US: 40 CFR Part 261, EU:91/156/EEC, JP: Waste Disposal and Cleaning Act, etc.).

Transport Information

UN Number 2604
Class 8/3
Packing Group I
HS Number 3822.00.5090

Application

t-Bu protection of Alcohols using Isobutylene

B0527

References

  • Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols
    • P. G. M. Wuts, in Greene’s Protective Groups in Organic Synthesis, 5th ed., ed. by P. G. M. Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17.

Deprotection of BOM Groups using Benzenethiol and Boron Trifluoride

B0527

References

  • Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols
    • P. G. M. Wuts, in Greene’s Protective Groups in Organic Synthesis, 5th ed., ed. by P. G. M. Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17.

BF3·Et2O Functioning as a Fluorine Source in an PhIO mediated Intermolecular Aminofluorination

B0527

Typical Procedure: To a solution of N-(but-3-en-1-yl)-4-methylbenzenesulfonamide (45 mg, 0.2 mmol) in CH2Cl2 (6 mL) in a flask are added BF3·Et2O (28.2 mg, 0.2 mmol) and PhIO (88 mg, 0.4 mmol). The reaction is stirred at room temperature for 4 h. The resulting mixture is diluted with ethyl acetate (50 mL). Then, the mixture is washed with sat. aqueous NaHCO3 (5 mL) and Na2S2O3 (5 mL). The separated aqueous phase is extracted with EtOAc (2×10 mL). The combined organic layer is washed with brine (10 mL), dried over MgSO4 and concentrated in vacuo to afford the crude product which is purified by flash column chromatography (Rf = 0.12, petroleum ether/EtOAc = 9/1) to give 3-fluoro-1-tosylpyrrolidine as a colorless solid (39 mg, 80% yield).

References

Stereoselective ring-opening hydrofluorination of aryl epoxides

Typical procedure: (RS,RS)-2-Methyl-3-phenyloxirane (4.5 g), BF3• OEt2 (1.38 mL) and CH2Cl2 (134 mL) were reacted at 20 ºC for 5 min. Saturated aqueous NaHCO3 was then added and the mixture was stirred vigorously until both layers became clear. The layers were separated and the organic phase was washed with sat. aq. NaHCO3. The combined aqueous phases were extracted twice with CH2Cl2 and the combined organic extracts were dried and concentrated in vacuo. The residue was purified by flash column chromatography (gradient elution, 5 % to 40 % EtOAc in 30~40 ºC petrol) gave (RS,RS)-1-fluoro-1-phenylpropane-2-ol as a colorless oil (4.31 g, 83 %, more than 99:1 dr).

References

Page Top