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Eprosartan Mesylate
(CAS RN:144143-96-4 Product Number:E1161)

Structure

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Eprosartan Mesylate
Synonym Eprosartan Methanesulfonate

General Information

Product Number E1161

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C23H24N2O4S·CH4O3S=520.62
CAS RN 144143-96-4
Related CAS RN 133040-01-4
MDL Number MFCD08141807
  • Product Details
  • Safety & Regulations
  • Reference & Application

Specification

Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 246.0 to 250.0 deg-C

References

Reaxys-RN 27406159
PubChem SID 253661215
Merck Index(14) 3635
RTECS# XN0282400

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P280
  • :Wear protective gloves, eye protection.
  • P302+P352+P332+P313+P362+P364
  • :If on skin: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Transport Information

HS Number 2934.99.3000

Application

Eprosartan mesylate: A Long-Lasting and Selective Angiotensin II Subtype 1 (AT1) Receptor Antagonist (Saltan)

Eprosartan mesylate (SKF 108566) is a potent, long-lasting and non-peptide selective angiotensin II subtype 1 (AT1) receptor antagonist (Saltan). Blocking of the AT1 receptor by a saltan (e.g. valsartan [V0112], irbesartan [I0859], eprosartan mesylate [E1161] and losartan potassium [L0232]) suppresses the action of angiotensin II which increases blood pressure in various ways. Eprosartan is not metabolized by the cytochrome P 450 system and therefore has a low potential for drug interactions. Eprosartan mesylate is used in the treatment of hypertension. (The product is for research purpose only.)

References

PubMed Literature

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