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Spectinomycin Dihydrochloride Pentahydrate
(CAS RN:22189-32-8 Product Number:S0584)

Structure

Spectinomycin Dihydrochloride

General Information

Product Number S0584

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Purity/Analysis Method >98.0%(N)(T)
Storage Temperature 0-10°C
M.F. / M.W. C14H24N2O7·2HCl·5H2O=405.27(as Anhydrous)
CAS RN 22189-32-8
Related CAS RN 1695-77-8,21736-83-4
MDL Number MFCD00150886
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Specification

Purity(with Total Nitrogen) min. 98.0 %(calcd.on anh.substance)
Purity(Argentmetric Titration) min. 98.0 %(calcd.on anh.substance)
Specific rotation [a]20/D +15.0 to +21.0 deg(C=1,H2O)
Water 16.0 to 20.0 %

Data of Reference

mp 207°C(dec.)(lit.)

References

PubChem SID 354335325
Merck Index(14) 8739
RTECS# WG7400000

Transport Information

HS Number 2941.90.1010

Application

Spectinomycin Dihydrochloride: An Aminocyclitol Antibiotic Used for the Treatment of Infection with Streptomyces spectabilis and for Molecular Cloning

Spectinomycin dihydrochloride is an aminoglycoside antibiotic produced by a species of soil microorganism designated as Streptomyces spectabilis. Spectinomycin exerts its bactericidal activity by inhibiting protein synthesis in the bacterial cell; the site of action is the 30S ribosomal subunit. Spectinomycin is highly effective for the treatment of infections with Neisseria gonorrhoeae. In vitro studies have shown no cross-resistance of Neisseria gonorrhoeae between spectinomycin hydrochloride and benzylpenicillins [A2092] [P1770] [P1772]. On bioscience research, a resistance-conferring gene for spectinomycin can also be used as a selection marker in bacteria for molecular cloning purposes. In addition, spectinomycin is used as a selection agent for transformed plant cells that contain the selectable marker gene SpcR. (The product is for research purpose only.)

References

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