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(CAS RN:2232-08-8 Product Number:T1985)


Synonym 1-Tosylimidazole

General Information

Product Number T1985

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Purity/Analysis Method >98.0%(HPLC)(N)
Storage Temperature
M.F. / M.W. C10H10N2O2S=222.26
CAS RN 2232-08-8
Related CAS RN
MDL Number MFCD00005285
  • Product Details
  • Safety & Regulations
  • Reference & Application


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Melting point 75.0 to 79.0 deg-C
Solubility in Methanol almost transparency


Beilstein 23(5)4,446
Reaxys-RN 612451
PubChem SID 87577678


Signal Word Warning
Hazard Statements
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P280
  • :Wear protective gloves, eye protection.
  • P302+P352+P332+P313+P362+P364
  • :If on skin: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Transport Information

HS Number 2933.29.4300


Esterification of Alcohols with Sodium Carboxylates

Experimental procedure: To a double-necked round bottom flask equipped with a condenser is added a mixture of alcohol (0.01 mol), TsIm (0.012 mol), TEA (0.015 mol), RCO2Na (0.02 mol) and a catalytic amount of TBAI (0.1 g) in DMF (30 mL). The mixture is refluxed until TLC monitoring indicates no further improvement in the conversion. The solvent is evaporated under vacuum and the remaining foam is dissolved in CHCl3 (100 mL) and subsequently washed with water (2 x 100 mL). The organic layer is dried (Na2SO4) and evaporated. The crude product is purified by column chromatography on silica gel eluting with a mixture of n-hexane/EtOAc to afford the desired ester.


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