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(±)-Thalidomide
(CAS RN:50-35-1 Product Number:T2524)

Structure

(+/-)-Thalidomide
Synonym N-(2,6-Dioxo-3-piperidinyl)phthalimide

General Information

Product Number T2524

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Purity/Analysis Method >98.0%(HPLC)(N)
Storage Temperature
M.F. / M.W. C13H10N2O4=258.23
CAS RN 50-35-1
Related CAS RN
MDL Number MFCD00153873
  • Product Details
  • Safety & Regulations
  • Reference & Application

Specification

Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %

Data of Reference

λmax 300(lit.)

References

Beilstein 22(5)13,224
Reaxys-RN 30233
PubChem SID 253662357
Merck Index(14) 9255
RTECS# TI4375000

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H301
  • :Toxic if swallowed.
  • H312
  • :Harmful in contact with skin.
  • H361
  • :Suspected of damaging fertility or the unborn child.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P202
  • :Do not handle until all safety precautions have been read and understood.
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P301+P310+P330
  • :If swallowed: Immediately call a poison center or doctor. Rinse mouth.
  • P302+P352+P312+P362+P364
  • :If on skin: Wash with plenty of soap and water. Call a poison center or doctor if you feel unwell. Take off contaminated clothing and wash it before reuse.
  • P308+P313
  • :If exposed or concerned: Get medical advice or attention.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents and container in accordance with local, regional, national regulations (e.g. US: 40 CFR Part 261, EU:91/156/EEC, JP: Waste Disposal and Cleaning Act, etc.).

Transport Information

UN Number 2811
Class 6.1
Packing Group III
HS Number 2925.19.4200

Application

Thalidomide: An Inhibitor of Angiogenesis

Thalidomide was originally used to treat morning sickness, but was banned as a human teratogen in the 1960s. In the 1990s, thalidomide has been discovered to have anti-inflammatory and anti-angiogenic properties, and is identified as an effective treatment for multiple myeloma. A recently approved amino analogue of thalidomide is pomalidomide [P2074]. (The product is for research purpose only.)

References

PubMed Literature

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