Methyl 2-(2,6-Dichloroanilino)phenylacetate
（CAS RN：15307-78-5 Numéro de Produit：M2903）
Structure
|
| Synonyme | 2-(2,6-Dichloroanilino)phenylacetic Acid Methyl Ester |
|---|---|
| Synonyme | Diclofenac Methyl Ester |
Spécification
| Purity(GC) | min. 97.0 % |
|---|---|
| Purity(with Total Nitrogen) | min. 97.0 % |
Données de référence
| mp | 102°C(lit.) |
|---|---|
| λmax | 272(MeOH)(lit.) |
Informations de transport
| Code Marchandise | 2922.49.2600 |
|---|
Application
A Methyl Ester of Diclofenac (NSAID, COX inhibitor)
Diclofenac methyl ester is a methyl ester of diclofenac [D3748] [D2508 (Na salt)] which is a nonsteroidal anti-inflammatory drug (NSAID) and a non-selective cyclooxygenase (COX) inhibitor. This methyl ester is reported as a prodrug of diclofenac and a synthetic intermediate of diclofenac analogs. (The product is for research purpose only.)
References
- Synthesis, Structure, and Activity of Diclofenac Analogues as Transthyretin Amyloid Fibril Formation Inhibitors
- Evaluation of diclofenac prodrugs for enhancing transdermal delivery
- Synthesis of various esters of diclofenac (NSAIDs) as pro-drugs and their biological evaluation
- Can diclofenac ester prodrug promote direct penetration across the skin?
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