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Carbohydrate-binding Proteins (Anti-Glyco Antibodies and Lectins) [Glyco-chemical Analysis]

 Carbohydrate chains are called the third life chain following the protein and the nucleic acid and are one of the most important issues in the post genome research. We support glycoscience research by providing useful anti-carbohydrate chain antibodies.
 Most carbohydrate chains attach to lipids or proteins and occur in the form of glycoproteins or glycolipids (N-glycan, O-glycan, proteoglycans and others). Carbohydrate chains are known to be expressed on brain, nerve, cancer, and endothelial cells. Some carbohydrate chains are known to relate to diseases (e.g., cancer, Alzheimer's disease, Guillain-Barré syndrome, Lysosome syndrome such as Fabry disease, gangliosidosis), differentiation and development (iPS/ES cells). Seasonal influenza viruses, annual epidemics that peak during winter, cause infection via cell-surface glycans. Anti-influenza virus drugs are structural mimics of sialic acid, because neuraminidase is a sialic acid hydrolase that is essential for the release of progeny virus particles from the surface of an infected cell.
 Antibodies are proteins which are one of the components of the immune system. The specificity of antibodies is likened to the interaction between a key and a keyhole. Antibodies are useful reagents for research in many scientific disciplines including life science and diagnostic reagents.
 Anti-carbohydrate antibodies can recognize glycolipids or glycoproteins. We mainly produce antibodies against glycolipids; ganglio series, globo series, lacto series, and neo-lacto series. These antibodies can be used for immunohistochemistry, cell-staining, inhibition assay for cell adhesion, flow cytometry, ELISA, TLC-immunostaining and other methods. Our antibodies are very useful tools for analyzing the expression of carbohydrate chains and their functions.
 Biotin-labeled anti-carbohydrate antibody is also available.
Anti-Glyco Antibodies
A2505
Anti-GM1 Monoclonal Antibody
A2506
Anti-Gb3 Monoclonal Antibody
A2507
Anti-GD1a Monoclonal Antibody
A2508
Anti-GD1b Monoclonal Antibody
A2509
Anti-Sialyl Lewis A Monoclonal Antibody (2D3)
A2510
Anti-Lewis Y Monoclonal Antibody
A2575
Anti-GM2 Monoclonal Antibody (Culture Supernatant)
A2576
Anti-GM2 Monoclonal Antibody
A2577
Anti-Lewis X Monoclonal Antibody (Culture Supernatant)
A2578
Anti-Lewis X Monoclonal Antibody
A2579
Anti-GD3 Monoclonal Antibody (Culture Supernatant)
A2580
Anti-GD3 Monoclonal Antibody
A2581
Anti-GM3 Monoclonal Antibody (Culture Supernatant)
A2582
Anti-GM3 Monoclonal Antibody
A2583
Anti-Sialyl Lewis A Monoclonal Antibody (1H4, Culture Supernatant)
A2584
Anti-Sialyl Lewis A Monoclonal Antibody (1H4)
A2586
Anti-Gb3 Monoclonal Antibody (Culture Supernatant)
A2587
Anti-Lewis Y Monoclonal Antibody (Culture Supernatant)
A2660
Anti-Sialyl Lewis X Monoclonal Antibody (Culture Supernatant)
A2662
Anti-GQ1b Monoclonal Antibody
A2701
Anti-GalNAc-GD1a Monoclonal Antibody
A2702
Anti-GT1a Monoclonal Antibody
A2706
Anti-SGPG(HNK-1) Monoclonal Antibody
A2732
Anti-GT1b Monoclonal Antibody
A2822
Anti-Gb3 Monoclonal Antibody Biotin Conjugate
A2849
Anti-Sialyl Lewis X Monoclonal Antibody
A2872
Anti-Chondroitin Sulfate D Monoclonal Antibody (MO-225)
A2968
Anti-Keratan Sulfate Monoclonal Antibody (R-10G)
A3123
Anti-α Gal Polyclonal Antibody (Chicken)
A3143
Anti-Chondroitin Sulfate A Monoclonal Antibody (LY111)
A3144
Anti-α Gal Polyclonal Antibody Biotin Conjugate
A3195
Anti-α Gal Chicken Polyclonal Antibody HRP Conjugate
A3240
Anti-NeuGc Chicken Polyclonal Antibody
A3251
Anti-6-sulfo LacNAc Monoclonal Antibody (AG105)
A3252
Anti-6,6'-disulfo LacNAc Monoclonal Antibody (L4L4-8)
A3253
Anti-Sialyl 6,6'-disulfo LacNAc Monoclonal Antibody (G270-16)
A3294
Anti-NeuGc Polyclonal Antibody Biotin Conjugate
A3295
Anti-NeuGc Polyclonal Antibody FITC Conjugate
A3337
Anti-α Gal Polyclonal Antibody FITC Conjugate
A3338
Anti-GD2 Monoclonal Antibody
A3342
Anti-Perlecan Monoclonal Antibody (HK-102)
A3354
Anti-α Gal Polyclonal Antibody R-PE Conjugate

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 Lectins are highly specific carbohydrate-binding proteins of nonimmune origin. Due to their ability to bind with cell-surface glycoproteins and glycolipids, lectins could agglutinate cells; they also could reversibly associate polysaccharides and glycoproteins in solution.
 Lectin has long been well-known as tools for detection and analysis of functional oligosaccharides in the glycoscience field. Recombinant lectins show better stability compared with lectins extracted from natural resources. TCI offers not only recombinant lectins but also chemically modified lectins such as several types of biotinylated lectin and lectin-agarose for detection and capturing of glycoconjugates.
Lectins

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