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CAS RN: 511296-88-1 | Product Number: C2826
Cyclic Pifithrin-α Hydrobromide
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Purity: >98.0%(HPLC)
Synonyms:
- 2-(p-Tolyl)-5,6,7,8-tetrahydroimidazo[2,1-b]benzothiazole Hydrobromide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
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|---|---|---|---|---|---|
| 100MG |
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| Product Number | C2826 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__6N__2S·HBr = 349.29 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| CAS RN | 511296-88-1 |
| PubChem Substance ID | 253659530 |
| Merck Index (14) | 7421 |
| MDL Number | MFCD02683960 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
| H.S.code* | 2934.99-000 |
Application
Mitophagy research
References
- Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic β-cell function in diabetes
- Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart
Application
p53 Inhibitors
References
- 1)Assessing TP53 status in human tumours to evaluate clinical outcome
- 2)Two supporting factors greatly improve the efficiency of human iPSC generation
- 3)Suppression of Induced pluripotent stem cell generation by the p53-p21 pathway
- 4)The Ink4/Arf locus is a barrier for iPS reprogramming
- 5)Linking the p53 tumour suppressor pathway to somatic cell reprogramming
- 6)Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
- 7)A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
- 8)p53, Stem cells, and reprogramming: tumor suppression beyond guarding the genome
- 9)A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy
PubMed Literature
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