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CAS RN: 75438-57-2 | Product Number: M2660
Moxonidine
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Purity: >98.0%(T)
Synonyms:
- 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
€47.00
|
1 | 5 |
|
|
| 1G |
€186.00
|
1 | 6 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | M2660 |
Purity / Analysis Method 
|
>98.0%(T) |
| Molecular Formula / Molecular Weight | C__9H__1__2ClN__5O = 241.68 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 75438-57-2 |
| Reaxys Registry Number | 6769959 |
| PubChem Substance ID | 253662597 |
| Merck Index (14) | 6293 |
| MDL Number | MFCD00865794 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 206 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | UV6260290 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2933599590 |
Application
選択的イミダゾリンl1受容体アゴニストでありα2-アドレナリン受容体アゴニストでもあるモキソニジン
Moxonidine is an imidazoline compound with selective agonist activity at imidazoline I1 receptors and only minor activity at α2-adrenoceptors. It is used for the treatment of hypertension as a centrally acting antihypertensive. (The product is for research purpose only.)
References
- Moxonidine, a centrally acting antihypertensive agent, is a selective ligand for I1-imidazoline sites
- Moxonidine, a selective α2-adrenergic and imidazoline receptor agonist, produces spinal antinociception in mice
- Moxonidine, a selective imidazoline/α2 adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice
- Central imidazoline (I1) receptors as targets of centrally acting antihypertensives: moxonidine and rilmenidine (a review)
- Moxonidine: a review of its use in essential hypertension
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