text.skipToContent text.skipToNavigation

TCI uses cookies to personalize and improve your user experience. By continuing on our website, you accept the use of cookies. You can change or update your cookiesettings at any time.

Maximum quantity allowed is 999

Please select the quantity
TCI Home

TCI Life Science News

February 2024

At TCI, we support discovery in life sciences through our knowledge and expertise in organic small molecules. This issue covers our life science topics as follows:


Cell Cycle Analysis Kit without Pre-Fixation

Cell Cycle Analysis Kit without Pre-Fixation

The cell cycle is a major target for various therapies, as it is directly responsible for cell proliferation. Cell cycle analysis is therefore an important tool for studying not only how cells proliferate, but also the therapeutic mechanisms underlying its regulation. The classic cell cycle assay requires cells to be pre-fixed with ethanol and treated with RNase, before finally being stained with DAPI or propidium iodide and analyzed. Depending on the cell line being used and the needs of the experimenter these extra steps can take anywhere from several hours to an entire day. However, the Cell Cycle Assay Kit (Red) [C3851] uses a special surfactant to permeabilize the cell membrane just enough for a DNA-specific fluorescent dye (7-AAD, λex, max = 549 nm, λem, max = 648 nm) to enter without DNA leaving the cell. In this way, analysis of the cell cycle can be performed without pre-fixation. Just collect your cells-of-interest, incubate with the included buffer / dye for as little as 15 minutes, and measure. Erastin: Inducer of Ferroptosis

Erastin: Inducer of Ferroptosis

Ferroptosis was reported by Stockwell et al. in 2012 as iron-dependent cell death mechanism separate from apoptosis. Ferroptosis is thought to be involved in various diseases such as neurodegenerative diseases and ischemia-reperfusion injury. Erastin [E1524] induces ferroptosis by inhibiting cystine uptake into the cell by the cystine transporter and decreasing the intracellular concentration of the antioxidant glutathione. Malondialdehyde Measurement Kit

Malondialdehyde Measurement Kit

Malondialdehyde (MDA), known as a degradation product of lipid peroxides, is used as a quantitative indicator of intracellular oxidative stress. Malondialdehyde measurement kit [M3637] helps to determine the malondialdehyde content by the Thiobarbituric Acid Reactive Substances (TBARS) method. Linear PEI for Gene Transfection

Linear PEI for Gene Transfection

Polyethyleneimine is a commonly used non-viral vector for gene transfection. We offer Linear PEI HCl [1mg/mL in PBS(-)] [for Transfection] [L0466] as a filter-sterilized ready-to-use solution. This product is deacylated for high transfection efficiency, and has negligible cytotoxicity.
» TCI eNewsletter Back Issues

How to Order TCI Products

To order, please contact your local distributor found below.

» Our distributors

* The prices displayed in the landing website are USD based catalog prices. TCI has specific website and local currency based price list for customers in South Korea, Singapore, and Australia. For customers in other Asia Pacific countries / regions, please visit our Asia Pacific Website and contact our local distributors for the end user's cost. (The USD prices that are shown in Asia Pacific websites are TCI's catalog prices.)
Please visit each country/region's website from the following links and confirm the prices. https://www.TCIchemicals.com

If you are interested in our biweekly e-enewsletter "TCI News" and want to receive regularly, please click the link below and sign up.
TCI News Sign-Up

Tokyo Chemical Industry Co., Ltd. (TCI)
Global Business Department
Customer Support and Technical service
» globalbusiness@TCIchemicals.com
» https://www.TCIchemicals.com
Session Status
Your session will timeout in 10 minutes. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page. minute. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page.
Continue Operation
Your session has timed out. You will be redirected to the HOME page.
Close