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CAS RN: 481-53-8 | Product Number: T2708
Tangeretin
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Purity: >96.0%(HPLC)
Synonyms:
- 4',5,6,7,8-Pentamethoxyflavone
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 10MG |
$19.00
|
Contact Us | 1 | ≥60 |
|
| 100MG |
$108.00
|
Contact Us | Contact Us | 30 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | T2708 |
Purity / Analysis Method 
|
>96.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__0O__7 = 372.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 481-53-8 |
| Reaxys Registry Number | 351695 |
| PubChem Substance ID | 125307389 |
| MDL Number | MFCD00017438 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Melting point | 153.0 to 157.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 155 °C |
GHS
Related Laws:
| RTECS# | DJ3102725 |
Transport Information:
| HS Number | 2932.99.7000 |
Application
Tangeretin: A Polymethoxylated Flavonoid with Anticancer and Antioxidant Activities
Tangeretin, a polymethoxylated flavonoid contained in peels of citrus fruits, is known to have anticancer and antioxidant activities. Recent studies have shown that tangeretin induces cell-cycle G1 arrest, and suppresses cyclooxygenase-2 (COX-2) expression. (The product is for research purpose only.)
References
- Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells
- Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells
- Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass? (a review)
- Tangeretin suppresses IL-1beta-induced cyclooxygenase (COX)-2 expression through inhibition of p38 MAPK, JNK, and AKT activation in human lung carcinoma cells
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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