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Discover Our New Products
Explore TCI's new products and its applications in the fields of Synthetic Chemistry, Analytical Chemistry, Life Science and Materials Science. We frequently update this page with new products information and more. Get up-to-date information on TCI's new product highlights!
New Products on Synthetic Chemistry
Thionylimide Derivatives for Synthesis of Sulfonimidamides
BiPhONSO and TrNSO are utilized in the one-pot synthesis of sulfonimidamides. BiPhONSO gives the corresponding sulfonimidamides when treated with a Grignard reagent and an amine. On the other hand, TrNSO is known to give sulfonimidamide via a chlorinated intermediate.
Bidentate Diamine Ligands for Cu-Catalyzed C-N Coupling
Aryl bromides are applicable to drug-like compounds containing heterocyclic rings. C-N coupling of aryl bromides with amines is possible using diamine bidentate ligands N-([1,1'-Biphenyl]-2-yl)-N'-(2-phenylnaphthalen-1-yl)benzene-1,2-diamine and N1-[3',5'-Di-tert-butyl-[1,1'-biphenyl]-2-yl]-N2-[2-(3,5-di-tert-butylphenyl)naphthalen-1-yl]benzene-1,2-diamine with copper salts at room temperature. Furthermore, N-([1,1'-Biphenyl]-2-yl)-N'-(2-phenylnaphthalen-1-yl)benzene-1,2-diamine has also been reported to be applicable to C-O coupling.
HPMC Capsule Reagents for Accelerating Synthetic Chemistry
- R0273
- Reagents for Metallophotoredox Cross-Coupling Reactions [NiBr2(dme), [Ir[dF(CF3)ppy]2(dtbbpy)]PF6, DABCO] (HPMC encapsulated)
- R0274
- Reagents for Condensation Reactions (EDCI·HCl, HOBt·H2O) (HPMC encapsulated)
- R0275
- Reagents for Suzuki-Miyaura Cross-Coupling Reactions [Pd(dppf)Cl2·CH2Cl2, Cs2CO3] (HPMC encapsulated)
TCI HPMC (hydroxypropyl methylcellulose) capsules lineup includes condensing reagents, reagents for photoredox reactions, and reagents for Suzuki-Miyaura cross-coupling reactions, which are frequently used in drug discovery research and synthetic organic chemistry, and the lineup is currently being expanded.
New Products on Materials Science
Acceptor Unit for Organic Semiconductors and Organic Conductors
3,7-Dihydrobenzo[1,2-b:4,5-b']difuran-2,6-dione is an electron acceptor unit that is recently being increasingly used. Polymers combining 3,7-Dihydrobenzo[1,2-b:4,5-b']difuran-2,6-dione with isatin derivatives have been reported to exhibit n-type semiconducting properties with an electron mobility 1 cm2V-1s-1 in air.
Trithiocarbonate-type RAFT Reagents for Precision Radical Polymerization
- T4240
- 2,2'-[Thiocarbonylbis(sulfanediyl)]bis(2-methylpropanoic Acid)
- C3994
- 2,2'-[Thiocarbonylbis(sulfanediyl)]dipropionic Acid
- C3995
- 3-[[[(1-Carboxyethyl)thio]carbonothioyl]thio]propanoic Acid
- B6646
- Benzyl Dodecyl Carbonotrithioate
- D6279
- 3,3'-[(Disulfanne-1,2-dicarbonothioyl)bis(sulfanediyl)]dipropionic Acid
- B6065
- Bis(dodecylsulfanylthiocarbonyl) Disulfide
New Products on Life Science
Fluorescent Dye Used as a Lysosomal Targeting Probe
Green DND-26 is a fluorescent dye that stains acidic organelles in living cells. Green DND-26 consists of a weak base moiety and a fluorophore, which emits strong fluorescence (Exmax: 504 nm, Emmax: 511 nm) by a selective accumulation in acidic cell organelles in living cells due to its weak base moiety. Lysosomes are one of the intracellular organelles responsible for the degradation of intracellular and extracellular components and contain various acidic degradation enzymes. Therefore, Green DND-26 is currently in use as a lysosomal targeting probe.
Endo-type Glycohydrolytic Enzymes "Endoglycosidase"
- A1651
- endo-β-N-Acetylglucosaminidase (=Endo-M) Recombinant: from Mucor hiemalis expressed in Candida boidinii (100m units/vial)
- E1339
- Endo-M-W251N Recombinant: from Mucor hiemalis expressed in Escherichia coli (500m units/vial)
- R0240
- rEGCase I
- R0241
- rEGCase I assisted by Activator II
- K0069
- Keratanase II from Bacillus circulans, Recombinant
The "endo-type" glycosidases which are known to cuts out oligosaccharides from the middle of a glycan chain. TCI has lined up a variety of endoglycosidases for diverse glycan analyses. They are gene-recombinant glycosidases and are already available for practical use in large quantities. Please use them as sophisticated research tools for cutting-edge glycoscience.
AMP-Activated Protein Kinase (AMPK) Activator
A769662 is a cell-permeable activator of AMP-activated protein kinase (AMPK). A769662 was found to directly stimulate partially purified rat liver AMPK with EC50 = 0.8 μM and inhibited fatty acid synthesis in primary rat hepatocytes with IC50 = 3.2 μM.
Magazine "TCIMAIL"
Find our latest magazine No.196 (August 2024) PDF [2.79 MB]