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CAS RN: 491-67-8 | Product Number: T2721
Baicalein
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Purity: >98.0%(T)
Synonyms:
- 5,6,7-Trihydroxyflavone
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 1G |
$188.00
|
2 | 1 | 6 |
|
| 5G |
$469.00
|
1 | 1 | 11 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | T2721 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__5H__1__0O__5 = 270.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 491-67-8 |
| Reaxys Registry Number | 272683 |
| PubChem Substance ID | 125307744 |
| Merck Index (14) | 942 |
| MDL Number | MFCD00017459 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 265 °C |
| Solubility (soluble in) | Dimethylformamide |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
| RTECS# | DJ3100898 |
Transport Information:
| HS Number | 2932.99.7000 |
Application
Efflux pump research
Baicalein has been reported to inhibit TetK tetracycline efflux pump.1) The compound also showed synergy with tetracycline in a MRSA strain that doesn’t possess tetK, or with β-lactams.
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Remarkable Synergies between Baicalein and Tetracycline, and Baicalein and β-Lactams against Methicillin-Resistant Staphylococcus aureus
- Baicalein Inhibits Staphylococcus aureus Biofilm Formation and the Quorum Sensing System In Vitro
- Virtual screening for novel quorum sensing inhibitors to eradicate biofilm formation of Pseudomonas aeruginosa
- Biological properties of baicalein in cardiovascular system (a review)
- New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin (a review)
- Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders (a review)
Application
Quorum sensing research / Biofilm research
References
Application
Baicalein: A Flavonoid with Various Pharmacological Activities Including Antioxidant and Anti-Tumor Activities
Baicalein is a flavonoid and one of the major constituent of the root of Scutellaria baicalensis, as well as wogonin [W0010] and baicalin [B2835]. Baicalein possesses a multitude of pharmacological activities. It has been reported that baicalein is a potent free radical scavenger and xanthine oxidase inhibitor, thus improving endothelial function and conferring cardiovascular protective actions against oxidative stress-induced cell injury. Furthermore, baicalein has potent anti- inflammatory and anti-tumor activities. Baicalein is cytotoxic to various human tumor cell lines in vitro and inhibit tumor growth in vivo. (The product is for research purpose only.)
References
PubMed Literature
Documents
Product Articles
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Safety Data Sheet (SDS)
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Specifications
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