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CAS RN: 66108-95-0 | Product Number: I0903
Iohexol (mixture of isomers)
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Purity: >98.0%(HPLC)(N)
Synonyms:
- N,N'-Bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodoisophthalamide (mixture of isomers)
- 5-[Acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide (mixture of isomers)
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| Product Number | I0903 |
Purity / Analysis Method 
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__9H__2__6I__3N__3O__9 = 821.14 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 66108-95-0 |
| Reaxys Registry Number | 2406632 |
| PubChem Substance ID | 253660591 |
| Merck Index (14) | 5052 |
| MDL Number | MFCD00077732 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 % (total of isomers) |
| Purity(with Total Nitrogen) | min. 98.0 % |
Properties (reference)
| Melting Point | 180 °C |
| Maximum Absorption Wavelength | 245 nm (H__2O) |
| Solubility in water | Soluble |
GHS
Related Laws:
| RTECS# | CZ2205000 |
Transport Information:
| H.S.code* | 2924.29-000 |
Application
Iohexol: A Water-Soluble Nonionic Radiographic Contrast Agent
Iohexol is a water-soluble nonionic contrast agent of low osmolality, commonly used in diagnostic radiography of the brain and spinal cord. Iohexol is also used for a marker for glomerular filtration rate (GFR): after intravenous injection, it is quantitatively recovered in the urine; the elimination occurs by glomerular filtration. It is called iohexol clearance test and used in a standard test of kidney function. For your reference, [A2169] is a key synthetic intermediate of it. (The product is for research purpose only.)
References
- Chemotoxicity of contrast media and clinical adverse effects: a review
- Iohexol: a review of its pharmacological properties and use as a contrast medium in myelography and neuroangiography
- Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate
- Evaluation of a single injection method, using iohexol, for estimating glomerular filtration rate in cats and dogs
- S. A. Brown, D. R. Finco, D. Boudinot, J. Wright, S. L. Tarver, T. Cooper, Am. J. Vet. Res. 1996, 57, 105.
- In Vivo Performance of a Liposomal Vascular Contrast Agent for CT and MR-Based Image Guidance Applications
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