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CAS RN: 288315-09-3 | Product Number: M2742
Methylcobalamin Hydrate
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Purity: >98.0%(N)
Synonyms:
- Mecobalamin Hydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
158,00 €
|
Ships within 2 weeks after ordering | ≥60 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | M2742 |
Purity / Analysis Method 
|
>98.0%(N) |
| Molecular Formula / Molecular Weight | C__6__3H__9__1CoN__1__3O__1__4P·xH__2O = 1,344.40 (as Anhydrous) |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 288315-09-3 |
| Related CAS RN
|
13422-55-4 |
| Reaxys Registry Number | 18144941 |
| PubChem Substance ID | 253661235 |
| MDL Number | MFCD00082483 |
Specifications
| Appearance | Red to Dark red to Brown powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 %(calcd.on anh.substance) |
| Water | max. 12.0 % |
Properties (reference)
| Solubility in water | Slightly soluble |
GHS
Related Laws:
| EC Number | 236-535-3 |
| RTECS# | GG3745000 |
Transport Information:
| HS Number | 2936260000 |
Application
ビタミンB12の生理学的等価体，メチルコバラミン
Methylcobalamin, a water soluble vitamin B12 analog, is equivalent physiologically to vitamin B12. Methylcobalamin functions as a coenzyme in a number of reactions, including the oxidation of fatty acids and the synthesis of DNA. It also works in conjugation with folic acid [F0043] (Vitamin B9) in the synthesis of the amino acid L-methionine [M0099] and it required for normal production of red blood cells. Although methylcobalamin is necessary for nervous system maintenance, the mechanisms are not entirely known. Methylcobalamin can be used to prevent or treat pathology arising from a lack of vitamin B12. (The product is for research purpose only.)
References
- How a protein binds B12: a 3.0 Å x-ray structure of B12-binding domains of methionine synthase
- Similarities and Differences between Cobalamins and Cobaloximes. Accurate Structural Determination of Methylcobalamin and of LiCl- and KCl-Containing Cyanocobalamins by Synchrotron Radiation
- Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency (a review)
- Cobalamin-dependent methyltransferases (a review)
- Vitamin B12-derivatives - enzyme cofactors and ligands of proteins and nucleic acids (a review)
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