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CAS RN: 518-82-1 | Product Number: E0500
Emodin
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Purity: >96.0%(HPLC)
Synonyms:
- 1,3,8-Trihydroxy-6-methylanthraquinone
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 100MG |
$98.00
|
1 | 1 | ≥40 |
|
| 1G |
$484.00
|
1 | 1 | 18 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | E0500 |
Purity / Analysis Method 
|
>96.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__0O__5 = 270.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 518-82-1 |
| Reaxys Registry Number | 1888141 |
| PubChem Substance ID | 87569750 |
| SDBS (AIST Spectral DB) | 21470 |
| Merck Index (14) | 3561 |
| MDL Number | MFCD00001207 |
Specifications
| Appearance | Orange to Amber to Dark red powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 253 °C(dec.) |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Tetrahydrofuran, Chloroform, Benzene, Alcohol, Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
| RTECS# | CB7920600 |
Transport Information:
| HS Number | 2914.69.9000 |
Application
Research for antifouling agent against aquatic organism
Reference
- Antifouling and antibacterial polyketides from marine gorgonian coral-associated fungus Penicillium sp. SCSGAF 0023
Application
Emodin: An Anthraquinone with a Wide Spectrum of Pharmacological Properties
Emodin is a natural occurring anthraquinone present in the roots and barks of numerous plants, molds, and lichens, and an active ingredient of various Chinese medicinal herbs. It has been reported that emodin has a wide spectrum of pharmacological properties, including diuretic, vasorelaxant, anti-bacterial, anti-viral, anti-ulcerogenic, anti-inflammatory, and anti-cancer effects. (The product is for research purpose only.)
References
- Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent (a review)
- Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer (a review)
- Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics
Application
Emodin: A Naturally Occurring Anthraquinone with Anti-Cancer and Anti-Inflammatory Activities
Emodin is a naturally occurring anthraquinone found in a variety of plants (e.g., rhubarb) used in traditional Chinese medicine.1,2) Purified emodin has been reported to possess diverse effects, including anti-oxidation, anti-cancer and anti-inflammatory activities. Emodin is a pleiotropic molecule capable of interacting with several major molecular targets including, NF-κB, casein kinase II, HER2/neu, HIF-1α, AKT/mTOR, STAT3, CXCR4, topoisomerase II, p53, p21, and androgen receptors which are involved in inflammation and cancer.2-4) (The product is for research purpose only.)
References
- 1) One single standard substance for the determination of multiple anthraquinone derivatives in rhubarb using high-performance liquid chromatography-diode array detection
- 2) Anti-cancer properties of anthraquinones from Rhubarb (a review)
- 3) Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent (a review)
- 4) Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer (a review)
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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