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CAS RN: 31282-04-9 | Product Number: H1509

Hygromycin B


Purity: >80.0%(HPLC)
Synonyms:
Documents:
200MG
$47.00
4   2   15  
1G
$160.00
1   4   17  

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Product Number H1509
Purity / Analysis Method >80.0%(HPLC)
Molecular Formula / Molecular Weight C__2__0H__3__7N__3O__1__3 = 527.52  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 31282-04-9
Reaxys Registry Number 66457
PubChem Substance ID 253661073
Merck Index (14) 4852
MDL Number

MFCD06795479

Specifications
Appearance White to Light yellow to Dark green powder to crystal
Purity(HPLC)(CAD) min. 80.0 area%
Specific rotation [a]20/D +18.0 to +23.0 deg(C=1, H2O)
Properties (reference)
Melting Point 180 °C(dec.)
Specific Rotation 20° (C=1,H2O)
Solubility in water Completely soluble
Solubility (very soluble in) Methanol,Ethanol
GHS
Pictogram Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H300 + H310 + H330 : Fatal if swallowed, in contact with skin or if inhaled.
H318 : Causes serious eye damage.
H317 : May cause an allergic skin reaction.
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P262 : Do not get in eyes, on skin, or on clothing.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P284 : Wear respiratory protection.
P272 : Contaminated work clothing must not be allowed out of the workplace.
P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P350 + P310 : IF ON SKIN: Gently wash with plenty of soap and water. Immediately call a POISON CENTER or doctor/ physician.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
P405 : Store locked up.
Related Laws: / Compliance with laws, Regulations
RTECS# WK2130000
Transport Information:
UN Number (DOT-AIR) UN3462
Class (DOT-AIR) 6.1
Packing Group (TCI-A) I
HS Number 2941.90.3000
Application
Hygromycin B: A Selective Reagent in Molecular Genetics Experiments on Cells

Hygromycin B is a water-soluble aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus. It is acts by binding to the 80S subunit of the bacterial ribosome and inhibiting protein synthesis. In molecular genetics, hygromycin B is used in genetic modification as a selective reagent to isolate prokaryotic and eukaryotic cells coupled to a gene coding for hygromycin resistance.

References


PubMed Literature


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