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CAS RN: 117946-91-5 | Product Number: L0316
Luzindole
×
Purity: >98.0%(HPLC)
Synonyms:
- N-Acetyl-2-benzyltryptamine
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|---|
| 25MG |
$185.00
|
1 | Ships from Philadelphia the same day* | 25 |
|
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| Product Number | L0316 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__0N__2O = 292.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 117946-91-5 |
| Reaxys Registry Number | 8156010 |
| PubChem Substance ID | 354335145 |
| MDL Number | MFCD00672498 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Melting point | 104.0 to 108.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 106 °C |
GHS
Related Laws:
| RTECS# | AC7765700 |
Transport Information:
| HS Number | 2933.99.8290 |
Application
Luzindole: A Selective MT2 Melatonin Receptor Antagonist
Luzindole (N-0774) is a G protein-coupled melatonin receptors (MT receptors) antagonist.1) Reportedly, luzindole acts as a selective melatonin receptor antagonist with approximately 11- to 25-fold greater affinity for the MT2 over the MT1 receptor.2,3) Therefore, luzindole is used to evaluate the roles of melatonin receptors.4) In addition, it is reported that luzindole has radical scavenging and antioxidant properties due to the chemical nature of the indoleamine.4,5) (cf. a related product: Melatonin [M1105])
References
- 1)Luzindole (N-0774): a novel melatonin receptor antagonist
- 2)Pharmacological characterization of human recombinant melatonin MT1 and MT2 receptors
- 3)Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms
- 4)Molecular tools to study melatonin pathways and actions (a review)
- 5)Melatonin receptor antagonist luzindole is a powerful radical scavenger in vitro
PubMed Literature
Product Articles
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