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CAS RN: 56-41-7 | Product Number: A0179
L-Alanine
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Purity: >99.0%(T)
Synonyms:
- L-2-Aminopropionic Acid
- H-Ala-OH
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25G |
€18.00
|
13 | ≥100 |
|
| 250G |
€125.00
|
8 | 17 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A0179 |
| Purity / Analysis Method | >99.0%(T) |
| Molecular Formula / Molecular Weight | C__3H__7NO__2 = 89.09 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 56-41-7 |
| Reaxys Registry Number | 1720248 |
| PubChem Substance ID | 87561861 |
| SDBS (AIST Spectral DB) | 1055 |
| Merck Index (14) | 204 |
| MDL Number | MFCD00064410 |
Specifications
| Appearance | White powder to crystal |
| Purity(Nonaqueous Titration) | min. 99.0 %(after drying) |
| Specific rotation [a]20/D | +14.0 to +15.0 deg(C=10, HCl)(after drying) |
| Solubility in Water | almost transparency |
Properties (reference)
| Melting Point | 315 °C(dec.) |
| Specific Rotation | 14° (C=10,HCl) |
GHS
Related Laws:
| EC Number | 200-273-8 |
| RTECS# | AY2990000 |
Transport Information:
| HS Number | 2922498590 |
Application
Bacterial spore germinant research
Bacterial spores are more resistant to antibiotics and nutritional deficiencies than their vegetative cells and sometimes cause serious problems from the viewpoint of hygiene in clinical treatment and food processing.1) Spore persistence also plays a major role in the recurrence of infections after antibiotic treatment. Molecules that stimulate germination are termed “germinants”1) and have been evaluated the efficacy of germinant administration combined with antibiotics (for example, reports by N. Budi et al.2,3)). L-Alanine has been reported to act as a germinant for spores of Clostridium botulinum, C. sporogenes etc.4-9)
(The product is for research purpose only.)
(The product is for research purpose only.)
References
- 1) Germinants and Their Receptors in Clostridia
- 2) Omadacycline Compared to Vancomycin When Combined with Germinants To Disrupt the Life Cycle of Clostridioides difficile.
- 3) Efficacy of Omadacycline or Vancomycin Combined With Germinants for Preventing Clostridioides difficile Relapse in a Murine Model
- 4) Functional Characterisation of Germinant Receptors in Clostridium botulinum and Clostridium sporogenes Presents Novel Insights into Spore Germination Systems
- 5) Mapping Interactions between Germinants and Clostridium difficile Spores
- 6) Spore germination of the psychrotolerant, red meat spoiler, Clostridium frigidicarnis
- 7) Requirements for Germination of Clostridium sordellii Spores In Vitro
- 8) The Effect of pH, Germinants and Temperature on the Germination of Spores of Clostridiurn bifermentans
- 9) Factors Affecting the Germination of Spores of Clostridium bifermentans
PubMed Literature
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