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Published TCIMAIL newest issue No.199
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CAS RN: 4871-97-0 | Product Number: C3439
Curcumol
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Purity: >98.0%(GC)
Synonyms:
- (3S,3aS,5S,6R,8aS)-Octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3a,6-epoxyazulen-6-ol
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 10MG |
€55.00
|
Contact Us | 6 |
|
| 50MG |
€195.00
|
Contact Us | 21 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C3439 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__5H__2__4O__2 = 236.36 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 4871-97-0 |
| Reaxys Registry Number | 4746140 |
| PubChem Substance ID | 354335520 |
| MDL Number | MFCD00272163 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 141.0 to 145.0 °C |
| Specific rotation [a]20/D | -36.0 to -39.5 deg(C=1, CHCL3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 143 °C |
| Specific Rotation | -38° (C=1,CHCl3) |
GHS
Related Laws:
Transport Information:
| HS Number | 2932990090 |
Application
Curcumol: A Natural Sesquiterpene with Various Bioactivities
Curcumol is a sesquiterpene originally isolated from Curcuma rhizomes which is a common traditional Chinese medicine.1,2) Pharmacological experiments have demonstrated the ability of the sesquiterpenes including curcumol to exhibit anti-oxidant3), anti-microbial4), anti-tumor4-6) and anti-inflammatory7) activities. (The product is for research purpose only.)
References
- 1)Fast determination of curcumol, curdione and germacrone in three species of Curcuma rhizomes by microwave-assisted extraction followed by headspace solid-phase microextraction and gas chromatography-mass spectrometry
- 2)Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry
- 3)Composition and antioxidant activity of the essential oil from Curcuma zedoaria
- 4)Antimicrobial activity and cytotoxicity of the essential oil of Curcuma zedoaria
- 5)Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae - A review
- 6)Curcumol induces apoptosis via caspases-independent mitochondrial pathway in human lung adenocarcinoma ASTC-a-1 cells
- 7)Curcumol exhibits anti-inflammatory properties by interfering with the JNK-mediated AP-1 pathway in lipopolysaccharide-activated RAW264.7 cells
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