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CAS RN: 70831-56-0 | Product Number: C3450
Chicoric Acid
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Purity: >98.0%(T)
Synonyms:
- (2R,3R)-2,3-Bis[[(E)-3-(3,4-dihydroxyphenyl)acryloyl]oxy]succinic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
82,00 €
|
2 | 25 |
|
|
| 50MG |
261,00 €
|
1 | 19 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C3450 |
Purity / Analysis Method 
|
>98.0%(T) |
| Molecular Formula / Molecular Weight | C__2__2H__1__8O__1__2 = 474.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
10MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 70831-56-0 |
| Reaxys Registry Number | 3229636 |
| PubChem Substance ID | 354335030 |
| MDL Number | MFCD22683653 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -360 to -400 deg(C=1, MeOH) |
Properties (reference)
| Melting Point | 206 °C |
| Specific Rotation | -370° (C=1,MeOH) |
| Maximum Absorption Wavelength | 327 nm |
GHS
Related Laws:
| RTECS# | EJ9852090 |
Transport Information:
| HS Number | 2918290090 |
Application
Chicoric Acid: A Phenylpropanoid with a Variety of Biological Effects including Anti-HIV Activity
Chicoric acid is a phenylpropanoid found in a number of plants, such as chicory (Cichorium intybus) and Echinacea (Echinacea purpurea), and reportedly has a variety of biological functions, such as antioxidant, anti-inflammatory, antiviral and analgesic activities, and antihyperglycemic effect.1-3) Recently, chicoric acid and its analogs are attracting attention to their anti-HIV activity as HIV-1 integrase inhibitors.4,5) (The product is for research purpose only.)
References
- 1)Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans
- 2)Effect of Chicoric Acid on Mast Cell-Mediated Allergic Inflammation in Vitro and in Vivo
- 3)Antihyperglycemic effect of a natural chicoric acid extract of chicory (Cichorium intybus L.): a comparative in vitro study with the effects of caffeic and ferulic acids
- 4)Chicoric Acid Analogs as HIV-1 Integrase Inhibitors
- 5)Chicoric acid and its analogues as an anti-HIV integrase agents (a review)
- 6)Pharmacokinetics, tissue distribution, and plasma protein binding study of chicoric acid by HPLC-MS/MS
PubMed Literature
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