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CAS RN: 149394-66-1 | Product Number: C3892
Cidofovir Dihydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (S)-[[[1-[4-Amino-2-oxopyrimidin-1(2H)-yl]-3-hydroxypropan-2-yl]oxy]methyl]phosphonic Acid Dihydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
€120.00
|
Contact Us | 13 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C3892 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__8H__1__4N__3O__6P·2H__2O = 315.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 149394-66-1 |
| Reaxys Registry Number | 25496604 |
| MDL Number | MFCD16556167 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Water | 11.0 to 12.0 % |
| NMR | confirm to structure |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H361 : Suspected of damaging fertility or the unborn child. H371 : May cause damage to organs. H341 : Suspected of causing genetic defects. H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. |
Related Laws:
Transport Information:
| HS Number | 2933599590 |
Application
Cidofovir: An Acyclic Nucleoside Phosphonate Analog with Activity against a Variety of DNA Viruses.
Cidofovir (HPMPC) is an acyclic nucleoside phosphonate analog with in vitro and in vivo activity against a variety of DNA viruses. There are reports that cidofovir has broad-spectrum antiviral activity against herpesviruses, papillomaviruses, polyomavirus, adenovirus, and poxvirus. Cidofovir undergoes intracellular activation to form its diphosphate, the active metabolite of cidofovir, which are potent inhibitors of viral DNA polymerases. (The product is for research purpose only.)
References
- (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication
- HPMPC (cidofovir), PMEA (adefovir) and related acyclic nucleoside phosphonate analogs: a review of their pharmacology and clinical potential in the treatment of viral infections (a review)
- Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections (a review)
- Acyclic nucleoside phosphonates: a key class of antiviral drugs (a review)
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