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Published TCIMAIL newest issue No.198
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CAS RN: 19130-96-2 | Product Number: D5612
1-Deoxynojirimycin
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Purity: >98.0%(HPLC)
Synonyms:
- (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol
- 1,5-Dideoxy-1,5-imino-D-glucitol
- Moranoline
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
€74.00
|
Contact Us | ≥40 |
|
| 250MG |
€253.00
|
2 | 18 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D5612 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__6H__1__3NO__4 = 163.17 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 19130-96-2 |
| Reaxys Registry Number | 1524395 |
| PubChem Substance ID | 468591452 |
| Merck Index (14) | 2905 |
| MDL Number | MFCD00063474 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
| Melting point | 201.0 to 205.0 °C |
| Specific rotation | +44.0 to +48.0 deg(C=1, water) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 203 °C |
GHS
Related Laws:
| RTECS# | TN4350300 |
Transport Information:
| HS Number | 2939799090 |
Application
1-Deoxynojirimycin: An α-Glucosidase Inhibitor
1-Deoxynojirimycin, an alkaloid azasugar, is a bioactive compound that exists in mulberry leaves and Commelina communis (dayflower) as well as from several bacterial strains. It has been reported that 1-deoxynojirimycin has diverse pharmacological properties as an α-glucosidase inhibitor, such as antihyperglycemic, anti-obesity, and antiviral activities.1,2) Furthermore, 1-deoxynojirimycin and its N-alkylated derivative (miglitol [M2302]: N-butyldeoxynojirimycin) have been used as α-glucosidase inhibitors that smooth post-prandial peak plasma glucose levels and thus improve glycemic control.3) (The product is for research purpose only.)
References
- 1) 1-deoxynojirimycin: occurrence, extraction, chemistry, oral pharmacokinetics, biological activities and in silico target fishing (a review)
- 2) Antiviral therapies targeting host ER alpha-glucosidases: Current status and future directions
- 3) N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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