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CAS RN: 1257-08-5 | Product Number: E0890
(-)-Epicatechin Gallate
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Purity: >98.0%(HPLC)
Synonyms:
- (-)-cis-3,3',4',5,7-Pentahydroxyflavane 3-Gallate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 20MG |
109,00 €
|
7 | ≥40 |
|
|
| 100MG |
350,00 €
|
Contact Us | 30 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | E0890 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__1__8O__1__0 = 442.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container
|
20MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1257-08-5 |
| Reaxys Registry Number | 65603 |
| PubChem Substance ID | 135727012 |
| MDL Number | MFCD00075936 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | -175.0 to -187.0 deg(C=1, EtOH) |
Properties (reference)
| Melting Point | 255 °C |
| Specific Rotation | -177° (C=1,EtOH) |
GHS
Related Laws:
| RTECS# | DH9030000 |
Transport Information:
| HS Number | 2932990090 |
Application
Gingipain inhibitor
Catechin derivatives, which included (-)-epigallocatechin gallate, (-)-epicatechin gallate, (-)-gallocatechin gallate, and (-)-catechin gallate, have been reported to inhibit Arg-gingipain (Rgp) in Porphyromonas gingivalis.1) The 50% inhibitory concentrations (IC50s) of these catechin derivatives for Rgp ranged from 3 to 5 μM. (-)-Epicatechin gallate is one of these derivatives. The compound was also shown to inhibit Lys-gingipain (Kgp), although weaker than Rgp.2)
(The product is for research purpose only.)
(The product is for research purpose only.)
References
- 1) Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis
- 2) Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids
- Determination of Tea Components with Antioxidant Activity
- Metabolism of green tea catechins: an overview
- Green tea extract: Chemistry, antioxidant properties and food applications - A review
- Antiviral effect of catechins in green tea on influenza virus
- Green Tea: Nature's Defense against Malignancies (a review)
- Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate
- Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes
- Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate
- Antioxidant properties of polyphenols extracted from green and black teas
Application
(-)-Epicatechin Gallate: A Components of Green Tea with a Variety of Biological Activities
(-)-Epicatechin gallate and (-)-epicatechin [E1226] are major components of green tea which is the most popular beverages worldwide. It has been reported that they possess a variety of biological activities, including antioxidant, anti-inflammatory, antiviral and anti-cancerous properties. (The product is for research purpose only.)
References
Application
Study of Componenst of Tea Polyphenols
References
PubMed Literature
Product Articles
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