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Published TCIMAIL newest issue No.199
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CAS RN: 42017-89-0 | Product Number: F1011
Fenofibric Acid
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Purity: >98.0%(GC)(T)
Synonyms:
- 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€33.00
|
1 | 9 |
|
| 5G |
€112.00
|
1 | 17 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | F1011 |
Purity / Analysis Method 
|
>98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__7H__1__5ClO__4 = 318.75 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 42017-89-0 |
| Reaxys Registry Number | 2058973 |
| PubChem Substance ID | 253661146 |
| MDL Number | MFCD00792461 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 179.0 to 183.0 °C |
Properties (reference)
| Melting Point | 181 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H411 : Toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P391 : Collect spillage. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 255-626-9 |
| RTECS# | UA2453000 |
Transport Information:
| UN Number | UN3077 |
| Class | 9 |
| Packing Group | III |
| HS Number | 2918999090 |
Application
Fenofibric Acid: An Activator of peroxisome proliferator activated receptor α(PPARα)
Fenofibric acid, an active form of fenofibrate [F0674], activates peroxisome proliferator activated receptor α (PPARα) to modify fatty acid and lipid metabolite. Therefore, fenofibric acid helps reduce lowering triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) levels, and increase low-density lipoprotein cholesterol (LDL-C) level in the blood. Fenofibric acid and fenofibrate are often co-administered with a HMG-CoA reductase inhibitor (statin) to the treatment of dyslipidemia. (The product is for research purpose only.)
References
- Fenofibric Acid, an Active Form of Fenofibrate, Increases Apolipoprotein A-I-Mediated High-Density Lipoprotein Biogenesis by Enhancing Transcription of ATP-Binding Cassette Transporter A1 Gene in a Liver X Receptor-Dependent Manner
- Fenofibric acid: In combination therapy in the treatment of mixed dyslipidemia (a review)
- Determination of bezafibrate, ciprofibrate and fenofibric acid in human plasma by high-performance liquid chromatography
- Stability indicating UPLC method for simultaneous determination of atorvastatin, fenofibrate and their degradation products in tablets
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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