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Published TCIMAIL newest issue No.198
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CAS RN: 60282-87-3 | Product Number: G0404
Gestodene
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Purity: >98.0%(HPLC)(qNMR)
Synonyms:
- 13β-Ethyl-17β-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
€50.00
|
1 | 5 |
|
| 1G |
€317.00
|
1 | 3 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | G0404 |
| Purity / Analysis Method | >98.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__1H__2__6O__2 = 310.44 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 60282-87-3 |
| Reaxys Registry Number | 4237181 |
| PubChem Substance ID | 253659751 |
| Merck Index (14) | 4413 |
| MDL Number | MFCD00867858 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 98.0 % |
| Melting point | 197.0 to 201.0 °C |
| Specific rotation [a]20/D | -179 to -185 deg(C=0.5,CHCl3) |
| Solubility in Chloroform | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 199 °C |
| Specific Rotation | -181° (C=0.5,CHCl3) |
| Maximum Absorption Wavelength | 240 nm (MeOH) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| EC Number | 262-145-8 |
| RTECS# | JF7956000 |
Transport Information:
| HS Number | 2937230000 |
Application
Studies on Pharmacology of Gestodene
References
- Comparative pharmacology of newer progestogens
- Gestodene: a review of its pharmacology, efficacy and tolerability in combined contraceptive preparations
- Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs
- Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene
- The estrogenic effects of gestodene, a potent contraceptive progestin, are mediated by its A-ring reduced metabolites
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