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Published TCIMAIL newest issue No.198
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CAS RN: 85999-40-2 | Product Number: H1742
23-Hydroxybetulinic Acid
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Purity: >98.0%(HPLC)
Synonyms:
- Anemosapogenin
- 3β,23-Dihydroxylup-20(29)-en-28-oic Acid
- (1R,3aS,5aR,5bR,7aR,8R,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-8-(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-(prop-1-en-2-yl)icosahydro-3aH-cyclopenta[a]chrysene-3a-carboxylic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5MG |
€85.00
|
Contact Us | 16 |
|
| 25MG |
€295.00
|
Contact Us | 20 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | H1742 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__3__0H__4__8O__4 = 472.71 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
| CAS RN | 85999-40-2 |
| Reaxys Registry Number | 8178643 |
| PubChem Substance ID | 468592022 |
| MDL Number | MFCD28126999 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 305 °C |
| Specific Rotation | 19° (C=1,CH2Cl2) |
GHS
Related Laws:
Transport Information:
| HS Number | 2918199890 |
Application
23-Hydroxybetulinic Acid: A Pentacyclic Triterpene with Anti-Tumor Activities
23-Hydroxybetulinic acid (23-HBA) is a pentacyclic triterpene is the major active constituent of Pulsatilla chinensis (Bunge) Regel used as an anti-inflammatory agent in traditional Chinese medicine. It has been reported that 23-HBA and its derivatives show a cytotoxic effect on multiple cancer cell lines. (The product is for research purpose only.)
References
- Triterpenoids from Pulsatilla chinensis
- A sensitive HPLC-MS/MS method for the simultaneous determination of anemoside B4, anemoside A3 and 23-hydroxybetulinic acid: Application to the pharmacokinetics and liver distribution of Pulsatilla chinensis saponins
- 23-Hydroxybetulinic acid-mediated apoptosis is accompanied by decreases in bcl-2 expression and telomerase activity in HL-60 Cells
- 23-Hydroxybetulinic acid from Pulsatilla chinensis (Bunge) Regel synergizes the antitumor activities of doxorubicin in vitro and in vivo
- Recent developments in the functionalization of betulinic acid and its natural analogues: a route to new bioactive compounds (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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