Published TCIMAIL newest issue No.198
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 117946-91-5 | Product Number: L0316
Luzindole
×
![]()
×
Purity: >98.0%(HPLC)
Synonyms:
- N-Acetyl-2-benzyltryptamine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€ 96,00
|
1 | 36 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | L0316 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__0N__2O = 292.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 117946-91-5 |
| Reaxys Registry Number | 8156010 |
| PubChem Substance ID | 354335145 |
| MDL Number | MFCD00672498 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Melting point | 104.0 to 108.0 °C |
Properties (reference)
| Melting Point | 106 °C |
GHS
Related Laws:
| RTECS# | AC7765700 |
Transport Information:
| HS Number | 2933998090 |
Application
Luzindole: A Selective MT2 Melatonin Receptor Antagonist
Luzindole (N-0774) is a G protein-coupled melatonin receptors (MT receptors) antagonist.1) Reportedly, luzindole acts as a selective melatonin receptor antagonist with approximately 11- to 25-fold greater affinity for the MT2 over the MT1 receptor.2,3) Therefore, luzindole is used to evaluate the roles of melatonin receptors.4) In addition, it is reported that luzindole has radical scavenging and antioxidant properties due to the chemical nature of the indoleamine.4,5) (cf. a related product: Melatonin [M1105])
References
- 1)Luzindole (N-0774): a novel melatonin receptor antagonist
- 2)Pharmacological characterization of human recombinant melatonin MT1 and MT2 receptors
- 3)Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms
- 4)Molecular tools to study melatonin pathways and actions (a review)
- 5)Melatonin receptor antagonist luzindole is a powerful radical scavenger in vitro
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.