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Published TCIMAIL newest issue No.198
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CAS RN: 23327-57-3 | Product Number: N1169
Nefopam Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€18.00
|
1 | 5 |
|
| 5G |
€56.00
|
2 | 28 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N1169 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__9NO·HCl = 289.80 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 23327-57-3 |
| Reaxys Registry Number | 3575294 |
| PubChem Substance ID | 468592495 |
| Merck Index (14) | 6440 |
| MDL Number | MFCD00012750 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 251 °C |
| Maximum Absorption Wavelength | 274 nm (H__2O) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| EC Number | 245-585-5 |
| RTECS# | DM4200000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2934999090 |
Application
Nefopam Hydrochloride: A Centrally Acting Non-Opioid Analgesic Agent
Nefopam hydrochloride is a non-opioid analgesic that possesses a profile distinct from that of anti-inflammatory agents. Although its mechanism of action is unclear, some reports suggest that nefopam probably produces its analgesic action through central acting mechanisms. (The product is for research purpose only.)
References
- Nefopam: a review of its pharmacological properties and therapeutic efficacy (a review)
- Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents
- Rediscovery of nefopam for the treatment of neuropathic pain (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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