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CAS RN: 92-84-2 | Product Number: P0106
Phenothiazine
×
Purity: >98.0%(GC)
Synonyms:
- 2,3:5,6-Dibenzo-1,4-thiazine
- Thiodiphenylamine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 25G |
€18.00
|
3 | ≥80 |
|
|
| 500G |
€35.00
|
≥100 | ≥40 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | P0106 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__2H__9NS = 199.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| CAS RN | 92-84-2 |
| Reaxys Registry Number | 143237 |
| PubChem Substance ID | 87574363 |
| SDBS (AIST Spectral DB) | 2068 |
| Merck Index (14) | 7252 |
| MDL Number | MFCD00005015 |
Specifications
| Appearance | White to Light yellow to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 183.0 to 188.0 °C |
| Solubility in Acetone | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 183 °C |
| Solubility in water | Insoluble |
| Degree of solubility in water | 1.59 mg/l 25 °C |
| Solubility (soluble in) | Ethanol, Ether |
| Solubility (slightly sol. in) | Alcohol |
| Solubility (insoluble in) | Chloroform |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H370 : Causes damage to organs. H373 : May cause damage to organs through prolonged or repeated exposure. H317 : May cause an allergic skin reaction. H335 : May cause respiratory irritation. H410 : Very toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P273 : Avoid release to the environment. P260 : Do not breathe dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P391 : Collect spillage. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. |
Related Laws:
| EC Number | 202-196-5 |
| RTECS# | SN5075000 |
Transport Information:
| UN Number | UN3077 |
| Class | 9 |
| Packing Group | III |
| HS Number | 2934309090 |
Application
Quorum sensing research
Phenothiazine has been reported to inhibit quorum sensing (QS) in Vibrio harveyi.1) The IC50 for autoinducer-1 (AI-1) is 4.6 ± 1.1 μM and the IC50 for autoinducer-2 (AI-2) is 7.4 ± 3.5 μM.
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) A new phenothiazine structural scaffold as inhibitors of bacterial quorum sensing in Vibrio harveyi
- A Novel and Specific NADPH Oxidase-1 (Nox1) Small-Molecule Inhibitor Blocks the Formation of Functional Invadopodia in Human Colon Cancer Cells
Application
NADPH oxidase-1 (NOX1) inhibitor
Reference
PubMed Literature
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