Published TCIMAIL newest issue No.199
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CAS RN: 54-42-2 | Product Number: I0258
5-Iodo-2'-deoxyuridine
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Purity: >99.0%(T)
Synonyms:
- Idoxuridine
- 5-Iododesoxyuridine
- IDU
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€41.00
|
1 | ≥60 |
|
|
| 5G |
€131.00
|
2 | ≥100 |
|
|
| 25G |
€509.00
|
4 | 34 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | I0258 |
Purity / Analysis Method 
|
>99.0%(T) |
| Molecular Formula / Molecular Weight | C__9H__1__1IN__2O__5 = 354.10 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 54-42-2 |
| Reaxys Registry Number | 30397 |
| PubChem Substance ID | 87571623 |
| SDBS (AIST Spectral DB) | 4820 |
| Merck Index (14) | 4891 |
| MDL Number | MFCD00134656 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 99.0 % |
| Specific rotation [a]20/D | +28.0 to +31.0 deg(C=1, 1mol/L NaOH sol.) |
| Solubility in hot Water | almost transparency |
Properties (reference)
| Specific Rotation | 30° (C=1,1mol/L NaOH sol.) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H361 : Suspected of damaging fertility or the unborn child. H341 : Suspected of causing genetic defects. |
| Precautionary Statements | P261 : Avoid breathing dust. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
Related Laws:
| EC Number | 200-207-8 |
| RTECS# | YU7700000 |
Transport Information:
| HS Number | 2934999090 |
Application
Idoxuridine: A Thymidine Analog and an Antiviral Agent against Herpes Simplex Virus (HSV)
Idoxuridine is a thymidine analog that is used as an antiviral agent against herpes simplex virus (HSV). Idoxuridine has a chemical structure similar to thymidine, except that the 5-methyl group is replaced by iodine. Herpes simplex virus utilizes thymidine in the synthesis of deoxyribonucleic acid (DNA). When idoxuridine is substituted for thymidine in the viral DNA, the viral is unable to replicate its DNA. (The product is for research purpose only.)
References
- Synthesis and biological activities of iododeoxyuridine, an analog of thymidine
- The effects of incorporation of 5-halogenated deoxyuridines into the DNA of eukaryotic cells (a review)
- Specific targets for antiviral drugs (a review)
PubMed Literature
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