CAS RN: 1668-10-6 | Product Number: G0253
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
|Purity / Analysis Method||>98.0%(T)|
|Molecular Formula / Molecular Weight||C__2H__6N__2O·HCl = 110.54|
|Physical State (20 deg.C)||Solid|
|Store Under Inert Gas||Store under inert gas|
|Condition to Avoid||Hygroscopic|
|Reaxys Registry Number||3554199|
|PubChem Substance ID||87570430|
|Appearance||White to Almost white powder to crystal|
|Purity(Argentometric Titration)||min. 98.0 %|
To a solution of Boc-ΔTyr(Cl2Bzl)-OH (307 mg, 0.7 mmol), glycinamide hydrochloride (77.4 mg, 0.7 mmol) and Et3N (0.1 mL, 0.7 mmol) in DMF (7 mL) is added EDC·HCl (148 mg. 0.77 mmol) and HOBt (129 mg, 0.84 mmol) at -10°C. The reaction mixture is stirred for 2 h at 0°C. and overnight at room temperature. After the solution is evaporated, the residual is dissolved in EtOAc. The solution is washed with 4% NaHCO3, 10% citric acid and water. The solution is dried and evaporated. The purification is carried out by silica gel column chromatography to give Boc-ΔTyr(Cl2Bzl)-Gly-NH2 (317 mg, 85% yield).
(Δ means dehydro-form.)
- Y. Shimohigashi, J. W. Dunning Jr., A. J. Kolar, C. H. Stamer, Int. J. Peptide Protein Res. 1983, 21, 202.
Safety Data Sheet (SDS)
The requested SDS is not available.
Please Contact Us for more information.
C of A & Other Certificates
The requested analytical chart is not available. Sorry for the inconvenience.