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CAS RN: 69123-98-4 | Product Number: D4200


Purity: >98.0%(HPLC)
  • Fialuridine
  • FIAU
  • 2'-Fluoro-5-iodoarauracil
3   ≥20 

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Product Number D4200
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__9H__1__0FIN__2O__5 = 372.09  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 69123-98-4
Reaxys Registry Number 892318
PubChem Substance ID 160871154
Merck Index (14) 4069
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 7.0 to 7.9 %
Properties (reference)
Melting Point 226 °C
Related Laws: / Compliance with laws, Regulations
RTECS# YQ9512500
Transport Information:
HS Number 2940000080
Studies of Antiviral Activity and Toxicity of Fialuridine

Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analog for chronic hepatitis B

R. McKenzie, M. W. Fried, R. Sallie, H. Conjeevaram, A. M. Di Bisceglie, Y. Park, B. Savarese, D. Kleiner, M. Tsokos, C. Luciano, T. Pruett, J. L. Stotka, S. E. Straus, J. H. Hoofnagle, N. Engl. J. Med. 1995, 333, 1099.

Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase

A. A. Johnson, A. S. Ray, J. Hanes, Z. Suo, J. M. Colacino, K. S. Anderson, K. A. Johnson, J. Biol. Chem. 2001, 276, 40847.

Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection

B. C. Tennant, B. H. Baldwin, L. A. Graham, M. A. Ascenzi, W. E. Hornbuckle, P. H. Rowland, I. A. Tochkov, A. E. Yeager, H. N. Erb, J. M. Colacino, C. Lopez, J. A. Engelhardt, R. R. Bowsher, F. C. Richardson, W. Lewis, P. J. Cote, B. E. Korba, J. L. Gerin, Hepatology 1998, 28, 179.

Review article: Mechanisms for the anti-hepatitis B virus activity and mitochondrial toxicity of fialuridine (FIAU)

J. M. Colacino, Antiviral Res. 1996, 29, 125.

PubMed Literature

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