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Published TCIMAIL newest issue No.199
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CAS RN: 317-34-0 | Product Number: A2805
Aminophylline
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25G |
€27.00
|
2 | 15 |
|
| 100G |
€74.00
|
4 | ≥40 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A2805 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__6N__8O__4·C__2H__8N__2 = 420.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 317-34-0 |
| Related CAS RN
|
58-55-9 |
| Reaxys Registry Number | 5783720 |
| PubChem Substance ID | 253662280 |
| Merck Index (14) | 465 |
| MDL Number | MFCD00013221 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 96.0 % |
Properties (reference)
| Melting Point | 272 °C |
| Solubility in water | Soluble |
| Solubility (slightly sol. in) | Methanol |
| Solubility (insoluble in) | Ether, Ethanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H317 : May cause an allergic skin reaction. |
| Precautionary Statements | P263 : Avoid contact during pregnancy and while nursing. P260 : Do not breathe dust. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 206-264-5 |
| RTECS# | XH5600000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2939590000 |
Application
Aminophylline: A Water Soluble Theophylline
Aminophylline is a compound of theophylline [T0179] with ethylenediamine [E0077] in 2:1 ratio to improve the solubility of theophylline in water. Aminophylline is used as a bronchodilator for treatment of asthma. (The product is for research purpose only.)
References
- Preliminary evaluation of the correlation between in vitro release and in vivo bioavailability of two aminophylline slow-release tablets
- Aminophylline (a review)
- Aminophylline (a review)
- Aminophylline treatment in severe, acute asthma. A meta-analysis
PubMed Literature
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