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Published TCIMAIL newest issue No.196
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TCI synthesizes various chemicals for drug discovery research in every stage. We offer small scale parallel synthesis, chemical library synthesis using combinatorial chemistry techniques with solid-phase and liquid-phase synthesis. Utilizing our own techniques, experience, and knowledge in manufacturing reagents, TCI offers middle to large scale synthesis for sample production. If your research calls for scaling-up, optimizing synthetic methods, or you simply need advice on compounds for your life science research based on chemical biology, TCI is here to help.
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Features
1) 20 years experience of GMP manufacturing
2) Library synthesis with using combinatorial chemistry
3) Available for FTE contract
What We Make and What We Do
Synthetic Target
- Pharmaceutical Raw Materials and Intermediates
- API
- Chemical Library
- API
- Chemical Library
Quantities
TCI can help you start with small quantities for laboratory testing, scale up for development, and finally go on to economical continuous manufacturing on the kilogram scale.
Multi-step Synthesis
TCI can multi-step synthesis of performance of up to 20 processes.
Example: Tricostatin A
Example: Tricostatin A
Chemical Library
Synthetic Target:
- Bioactive Compound
- Low Molecular Organic Compound
- Metabolite/Degradation Product
- Stable isotope-labeled Compounds
- Fluorescent Labeled Compound
Number of compounds available for synthesis: 1 - 1,000
Quantities: Milligram to Gram scale and available to up to kilogram scale
- Bioactive Compound
- Low Molecular Organic Compound
- Metabolite/Degradation Product
- Stable isotope-labeled Compounds
- Fluorescent Labeled Compound
Number of compounds available for synthesis: 1 - 1,000
Quantities: Milligram to Gram scale and available to up to kilogram scale
Exploratory Research
Backed by numerous synthetic achievements, TCI designs and synthesizes the chemical library with our own unique know-how. If your lab requires hard-to-synthesize compounds, such as a probe for clarifying action mechanisms, our exploratory research division can help guide you through the process.
Synthetic Techniques Based on Combinatorial Chemistry
We have introduced synthetic techniques based on combinatorial chemistry to synthesize various compounds efficiently. TCI synthesizes many structurally distinct compounds and achieves high-throughput screened results.
Focused Library
TCI offers solutions not only for the synthesis of the chemical library, but also for related libraries as well.
Development Research
Lead Optimization
TCI manufacturing expertise allows us to optimize the structure with incredible detail.
Process Chemistry
We optimize the structure with compounds acquired from years of exploratory research. Additionally, improvements of synthetic methods allows for scale-up as well as previously undefined synthetic processes.
Pharmaceutical Technology
We offer intermediates, reagents, and produce investigational drugs using GMP compliance based on decades of manufacturing expertise.
Producing
TCI has production results of API products. Having established the production system that utilizes these resources, TCI is able to provision materials and key intermediates.