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CAS RN: 26148-68-5 | Product Number: A3209
2-Amino-9H-pyrido[2,3-b]indole
![Thumbnail of 2-Amino-9H-pyrido[2,3-b]indole](/medias/A3209.jpg?context=bWFzdGVyfHJvb3R8MTQ2MDB8aW1hZ2UvanBlZ3xhREU1TDJoak5DODRPVE16TVRjeU5qUXhPREl5TDBFek1qQTVMbXB3Wnd8NWRkYzg0OWIyYWU1NjNmMWFlNTE4MTUzMDUyNmIxMDU0NGM4MmM4YTA0MTJlNGM3YzEzZDRiMDMyMTU4MGMwZg "2-Amino-9H-pyrido[2,3-b]indole")
![Chemical Structure of 2-Amino-9H-pyrido[2,3-b]indole](/medias/A3209.jpg?context=bWFzdGVyfHJvb3R8NDU4OTN8aW1hZ2UvanBlZ3xhR1kwTDJoak5pODRPVEU1TnpNd05UVXlPRFl5TDBFek1qQTVMbXB3Wnd8ZTk4NjFjMGQzOWQ2Y2JlMDRkOTBlZTEyNzk4NTg2NWRiNjg2NzhmYjg0MzcwOWIxZGM4MGRiNWE4ODFhMGUxOQ "2-Amino-9H-pyrido[2,3-b]indole")
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![2-Amino-9H-pyrido[2,3-b]indole](/_ui/responsive/theme-tci/images/missing_product_zoom.webp "2-Amino-9H-pyrido[2,3-b]indole")
Purity: >98.0%(GC)
Synonyms:
- 9H-1,9-Diazafluoren-2-amine
- 9H-Pyrido[2,3-b]indol-2-amine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
€58.00
|
1 | 25 |
|
|
| 25MG |
€193.00
|
Contact Us | 25 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | A3209 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__1H__9N__3 = 183.21 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 26148-68-5 |
| Reaxys Registry Number | 744369 |
| PubChem Substance ID | 468590169 |
| MDL Number | MFCD00210750 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 199.0 to 203.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 201 °C |
| Boiling Point | 441 °C |
| Maximum Absorption Wavelength | 337 nm (MeOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H341 : Suspected of causing genetic defects. H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | UU9351600 |
Transport Information:
| HS Number | 2933998090 |
Application
A Mutagenic and Carcinogenic Heterocyclic Amine
2-Amino-9H-pyrido[2,3-b]indole (its other name: 2-amino-α-carboline) is a mutagenic and carcinogenic heterocyclic amine present in foods cooked at high temperature and in cigarette smoke. Scientific reports have been suggested that it’s active metabolites form covalent DNA adducts, and may be a significant source of DNA damage.
References
- Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research
- In vitro bioactivation of N-hydroxy-2-amino-α-carboline
- Quantitation of mutagenic/carcinogenic heterocyclic aromatic amines in food products
- Two food-borne heterocyclic amines: Metabolism and DNA adduct formation of amino-α-carbolines (a review)
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