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Published TCIMAIL newest issue No.201
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CAS RN: 50-32-8 | Product Number: B0085
3,4-Benzopyrene (purified by sublimation)
Purity: >95.0%(GC)
Synonyms:
- Benzo[a]pyrene (purified by sublimation)
Product Documents:
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| Product Number | B0085 |
Purity / Analysis Method
|
>95.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__0H__1__2 = 252.32 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 50-32-8 |
| Reaxys Registry Number | 1911333 |
| PubChem Substance ID | 87563286 |
| SDBS (AIST Spectral DB) | 3308 |
| Merck Index (14) | 1103 |
| MDL Number | MFCD00003602 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 176.0 to 180.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 176 °C |
| Boiling Point | 496 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Toluene, Benzene, Ether |
| Solubility (slightly sol. in) | Alcohol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H373 : May cause damage to organs through prolonged or repeated exposure. H317 : May cause an allergic skin reaction. H340 : May cause genetic defects. H350 : May cause cancer. H360FD : May damage fertility. May damage the unborn child. H410 : Very toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P501 : Dispose of contents/container to .?. P273 : Avoid release to the environment. P260 : Do not breathe dust. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P391 : Collect spillage. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. |
Related Laws:
| EC Number | 200-028-5 |
| RTECS# | DJ3675000 |
Transport Information:
| UN Number | UN3077 |
| Class | 9 |
| Packing Group | III |
| HS Number | 2902900000 |
Application
Reagent for lung carcinoma model
References
- Induction of benign and malignant pulmonary tumours in mice with benzo(a)pyrene.
- S. H. Kim, C. S. Lee, Anticancer Res. 1996, 16, 1, 465.
- Effect of all-trans retinoic acid (ATRA) on syndecan-1 expression and its chemoprotective effect in benzo(α)pyrene-induced lung cancer mice model.
- Use of p53 transgenic mice in the development of cancer models for multiple purposes.
- Capsaicin inhibits benzo(a)pyrene-induced lung carcinogenesis in an in vivo mouse model.
PubMed Literature
Documents
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