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Published TCIMAIL newest issue No.201
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CAS RN: 1077-28-7 | Product Number: L0058
DL-α-Lipoic Acid
Purity: >99.0%(T)
Synonyms:
- DL-Thioctic Acid
Product Documents:
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| Product Number | L0058 |
Purity / Analysis Method
|
>99.0%(T) |
| Molecular Formula / Molecular Weight | C__8H__1__4O__2S__2 = 206.32 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Hygroscopic,Heat Sensitive |
| CAS RN | 1077-28-7 |
| Reaxys Registry Number | 81851 |
| PubChem Substance ID | 87572024 |
| SDBS (AIST Spectral DB) | 10401 |
| Merck Index (14) | 9326 |
| MDL Number | MFCD00005474 |
Specifications
| Appearance | Light orange to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 99.0 % |
Properties (reference)
| Boiling Point | 165 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Toluene, Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 214-071-2 |
| RTECS# | JP1192000 |
Transport Information:
| HS Number | 2934999061 |
Application
α-Lipoic acid: A Powerful Antioxidant and a Radical Scavenger
α-Lipoic acid and its reduced form, dihydrolipoic acid [D4586], are powerful antioxidants. α-Lipoic acid also scavenges hydroxyl radicals, hypochlorous acid, peroxynitrite, and singlet oxygen. Dihydrolipoic acid is a racemic compound but the R-enantiomer is thought to be more bioavailable compared to the S-enantiomer.
References
- Neuroprotection by the metabolic antioxidant α-lipoic acid
- The pharmacology of the antioxidant lipoic acid (a review)
- Molecular aspects of lipoic acid in the prevention of diabetes complications (a review)
- Antioxidant and Prooxidant Activities of α-Lipoic Acid and Dihydrolipoic Acid (a review)
- Lipoic acid as a novel treatment for Alzheimer's disease and related dementias (a review)
- Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential (a review)
PubMed Literature
Product Articles
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