Published TCIMAIL newest issue No.201
Maximum quantity allowed is 999
CAS RN: 84057-84-1 | Product Number: L0241
Lamotrigine
Purity: >98.0%(T)(HPLC)
- 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
- 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine
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| Product Number | L0241 |
Purity / Analysis Method
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__9H__7Cl__2N__5 = 256.09 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 84057-84-1 |
| Reaxys Registry Number | 7589268 |
| PubChem Substance ID | 160871245 |
| Merck Index (14) | 5353 |
| MDL Number | MFCD00865333 |
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 216.0 to 220.0 °C |
| NMR | confirm to structure |
| Melting Point | 218 °C |
| Solubility (soluble in) | Dimethylformamide |
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
| EC Number | 281-901-8 |
| RTECS# | XY5850700 |
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2933698090 |
文献
- Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action
- Interaction of the antiepileptic drug lamotrigine with recombinant rat brain type IIA Na+ channels and with native Na+channels in rat hippocampal neurons
- An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels
- H. Cheung, D. Kamp, E. Harris, Epilepsy Res. 1992, 13, 107.
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