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Published TCIMAIL newest issue No.201
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CAS RN: 476-28-8 | Product Number: L0445
Lycorine
Purity: >98.0%(T)(HPLC)
Synonyms:
- (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol
Product Documents:
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| Product Number | L0445 |
Purity / Analysis Method
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__7NO__4 = 287.32 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
Packaging and Container
|
250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 476-28-8 |
| Reaxys Registry Number | 93605 |
| MDL Number | MFCD00221746 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Volumetric Analysis) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
| EC Number | 207-503-6 |
| RTECS# | OL2900000 |
Transport Information:
| HS Number | 2939799090 |
Application
Lycorine: The Major Bioactive Alkaloid Found in Amaryllidaceae Family Plant
Lycorine is the major bioactive alkaloid found in Amaryllidaceae family plant, a represent traditional Chinese medicinal herb. Lycorine and its derivatives have been shown to have various biological activities, including anti-leukemia, anti-tumor, anti-angiogenesis, anti-virus, anti-bacteria, anti-inflammation, and anti-malaria. They also exert many biological functions such as inhibition of acetylcholinesterase and protection of internal organs in sepsis. (The product is for research purpose only.)
References
- Lycorine and its derivatives for anticancer drug design (a review)
- Multiple biological functions and pharmacological effects of lycorine (a review)
- Amaryllidaceae alkaloids: Absolute configuration and biological activity (a review)
- Lycorine: A prospective natural lead for anticancer drug discovery (a review)
- Lycorine and organ protection: Review of its potential effects and molecular mechanisms
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