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CAS RN: 154-42-7 | Product Number: T0212

6-Thioguanine


Purity: >95.0%(HPLC)
Synonyms:
  • 2-Amino-6-mercaptopurine
  • 6-Mercaptoguanine
Documents:
1G
£37.00
3   ≥20 
5G
£136.00
1   15  

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number T0212
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__5H__5N__5S = 167.19  
Physical State (20 deg.C) Solid
CAS RN 154-42-7
Reaxys Registry Number 1074099
PubChem Substance ID 87576202
SDBS (AIST Spectral DB) 4204
Merck Index (14) 9337
MDL Number

MFCD00233553

Specifications
Appearance Light orange to Yellow to Green powder to crystal
Purity(HPLC) min. 95.0 area%
Properties (reference)
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
Related Laws: / Compliance with laws, Regulations
Enzyme Commission 205-827-2
RTECS# UP0740000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
HS Number 2933998090
Application
6-Thioguanineis: A Cytotoxic Agent with Immunosuppressive and Antitumor Properties

T0212

6-Thioguanine (6-TG) is a cytotoxic agent with immunosuppressive and antitumor properties. In cell, 6-TG is converted to the active nucleotide metabolite by the enzyme hypoxanthine guanine phosphoribosyltransferase (HPRT), subsequently leading to inhibition of DNA/RNA synthesis.

References


PubMed Literature


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