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CAS RN: 95233-18-4 | Product Number: A2545
Atovaquone
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Purity: >98.0%(T)(HPLC)
Synonyms:
- trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione
- Atavaquone
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
€42.00
|
1 | 31 |
|
|
| 1G |
€149.00
|
9 | ≥40 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | A2545 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__1__9ClO__3 = 366.84 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 95233-18-4 |
| Reaxys Registry Number | 8076827 |
| PubChem Substance ID | 160871512 |
| Merck Index (14) | 866 |
| MDL Number | MFCD00889188 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 220.0 to 224.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 223 °C |
| Maximum Absorption Wavelength | 494 nm (aq. Buffer) |
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Acetone |
| Solubility (insoluble in) | Methanol |
GHS
| Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
| RTECS# | QJ5616500 |
Transport Information:
| HS Number | 2914790090 |
Application
Atovaquone: An Antifungal Reagent against Pneumocystis jiroveci
(The product is for research purpose only.)
References
- Atovaquone - a novel broad-spectrum anti-infective drug (a review)
- New Insights Into Transmission, Diagnosis, and Drug Treatment of Pneumocystis carinii Pneumonia (a review)
- Chemotherapy against babesiosis (a review)
Application
Studies on Antimicrobial and Antimalarial Activities of Atovaquone
References
- Atovaquone, a broad spectrum antiparasitic drug, collapses mitochondrial membrane potential in a malarial parasite
- Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites
- Interactions of atovaquone with other antimalarial drugs against Plasmodium falciparum in vitro
- A mechanism for the synergistic antimalarial action of atovaquone and proguanil
- I. K. Srivastava, A. B. Vaidya, Antimicrob. Agents Chemother. 1999, 43, 1334.
- Antiparasitic agent atovaquone
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