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CAS RN: 55779-18-5 | Product Number: A3146
Arprinocid
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Purity: >95.0%(HPLC)
Synonyms:
- 9-(2-Chloro-6-fluorobenzyl)-9H-purin-6-amine
- Arpocox
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
€42.00
|
1 | 2 |
|
| 250MG |
€149.00
|
Contact Us | 9 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A3146 |
Purity / Analysis Method 
|
>95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__2H__9ClFN__5 = 277.69 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 55779-18-5 |
| Reaxys Registry Number | 827813 |
| PubChem Substance ID | 354333137 |
| MDL Number | MFCD00867210 |
Specifications
| Appearance | White to Yellow to Orange powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Elemental analysis(Nitrogen) | 24.00 to 26.50 % |
| Melting point | 242.0 to 247.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 245 °C |
| Maximum Absorption Wavelength | 260 nm (NaOH aq.) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 259-817-8 |
Transport Information:
| HS Number | 2933998090 |
Application
Arprinocid: An Anticoccidial Agent against Toxoplasma gondii
Arprinocid is an anticoccidial agent. Arprinocid and its main metabolite, arprinocid-1-N-oxide, have been found to exert cidal effect on Toxoplasma gondii in vitro. However, the exact mechanism of action is unknown. (The product is for research purpose only.)
References
- Potent in vivo activity of arprinocid, a purine analog against murine toxoplasmosis
- Toxoplasma gondii: in vivo and in vitro studies of a mutant resistant to arprinocid-N-oxide
- Determination of 20 coccidiostats in milk, duck muscle and non-avian muscle tissue using UHPLC-MS/MS
Application
Aprinocid: A Potent Anticoccidial Agent
Aprinocid and its metabolite arprinocid-1-N-oxide [55779-19-6] exhibit potent anticoccidial activity. It is reported that they are interfere with the hypoxanthine and guanine acquisition by Eimeria. (The product is for research purpose only.)
References
- Arprinocid, an inhibitor of hypoxanthine-guanine transport
- A comparative study of the biological activities of arprinocid and arprinocid-1-N-oxide
- Potent in vivo activity of arprinocid, a purine analog against murine toxoplasmosis
- Resistance to anticoccidial drugs : Alternative strategies to control coccidiosis in broilers (a review)
- Determination of 20 coccidiostats in egg and avian muscle tissue using ultra high performance liquid chromatography-tandem mass spectrometry
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