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Published TCIMAIL newest issue No.201
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CAS RN: 14919-77-8 | Product Number: B4108
Benserazide Hydrochloride
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Purity: >97.0%(T)(HPLC)
Synonyms:
- DL-Serine 2-(2,3,4-Trihydroxybenzyl)hydrazide Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 1G |
54,00 €
|
1 | 21 | |
| 5G |
174,00 €
|
1 | ≥40 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | B4108 |
Purity / Analysis Method 
|
>97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__5N__3O__5·HCl = 293.70 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Hygroscopic |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 14919-77-8 |
| Related CAS RN
|
322-35-0 |
| Reaxys Registry Number | 6494463 |
| PubChem Substance ID | 253659990 |
| Merck Index (14) | 1050 |
| MDL Number | MFCD00078571 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
Properties (reference)
| Melting Point | 180 °C(dec.) |
| Maximum Absorption Wavelength | 272 nm (HCl aq.) |
| Solubility in water | Soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 238-991-9 |
| RTECS# | VT9632300 |
Transport Information:
| HS Number | 2928009090 |
Application
Benserazide: An Aromatic L-Amino Acid Decarboxylase or L-DOPA Decarboxylase Inhibitor
Benserazide is an aromatic L-amino acid decarboxylase or L-DOPA [D0600] decarboxylase inhibitor, which is unable to cross the blood–brain barrier.
References
- Antiparkinsonian effect of a new selective adenosine A2A receptor antagonist in MPTP-treated monkeys
- Simultaneous determination of levodopa and benserazide by stopped-flow injection analysis and three-way multivariate calibration of kinetic-spectrophotometric data
- Dopamine D1 and D2 receptor contributions to L-DOPA-induced dyskinesia in the dopamine-depleted rat
- The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson's disease
- In-vitro and in-vivo inhibition by benserazide of clorgyline-resistant amine oxidases in rat cardiovascular tissues
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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