Maximum quantity allowed is 999
Please select the quantity
CAS RN: 125-84-8 | Product Number: A1947
DL-Aminoglutethimide
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 3-(4-Aminophenyl)-3-ethylpiperidine-2,6-dione
Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
More Stock Info
|
|---|---|---|---|---|---|
| 1G |
¥2,700
|
13 | |||
| 5G |
¥8,700
|
Ship in 2-3 business days after ordering |
|||
| 25G |
¥29,500
|
2 | 6 |
* Please check with "Check Estimated Ship Date" for details. The shipping date may vary depending on the quantity.
* For the case that without specific estimated shipping data, e.g.: If displayed as "will be shipped after 8 working days", the products will be shipped 8 working days later after ordering.
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock in other WH: 2-3 Business Days
* Please contact us if you need further information.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* For the case that without specific estimated shipping data, e.g.: If displayed as "will be shipped after 8 working days", the products will be shipped 8 working days later after ordering.
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock in other WH: 2-3 Business Days
* Please contact us if you need further information.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 150.0 to 154.0 °C |
| Solubility in Acetone | very faint turbidity |
Properties (reference)
| Melting Point | 152 °C |
| Solubility (soluble in) | Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | MA4026950 |
Transport Information:
Application
DL-Aminoglutethimide: A Potent but Nonselective Aromatase Inhibitor
DL-Aminoglutethimide is a first generation, and a potent but nonselective aromatase inhibitor. Aminoglutethimide inhibits the enzymatic side-chain cleavage of cholesterol [C0318] to pregnenolone [P0786], mediated through the binding of aminoglutethimide to cytochrome P 450， resulting in a decrease in the production of adrenal glucocorticoids, mineralocorticoids, estrogens, and androgens. Besides, aminoglutethimide-P450 complexes block enzymatic 11- and 18-hydroxylation steps required for the aromatization of androgens to estrogens. Aminoglutethimide is used for the treatment of Cushing’s syndrome, breast and prostate cancer. (The product is for research purpose only.)
References
- Aminoglutethimide (Elipten) as an inhibitor of adrenal steroidogenesis: mechanism of action and therapeutic trial
- Stereoselective inhibition of aromatase by enantiomers of aminoglutethimide
- Regulation of intramitochondrial cholesterol transfer to side-chain cleavage cytochrome P-450 in rat adrenal gland
- Mechanisms of action of aminoglutethimide as endocrine therapy of breast cancer (a review)
- History of aromatase: saga of an important biological mediator and therapeutic target
PubMed Literature
Articles/Brochures
TCIMAIL
Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.